Amlodipine/Olmesartan (Azor): Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Uses

What is amlodipine/olmesartan used for?

Amlodipine/olmesartan is commonly used to treat high blood pressure (hypertension).

Amlodipine/olmesartan may also be used for other conditions as determined by your healthcare provider.

How does amlodipine/olmesartan work (mechanism of action)?

Amlodipine and olmesartan relax your blood vessels so that blood can move through them more easily.

This can help lower blood pressure and may reduce your risk for heart attack and stroke.

How is amlodipine/olmesartan supplied (dosage forms)?

Brands and other names

Azor

Dosage forms and strengths

5 mg/20 mg, 5 mg/40 mg, 10 mg/20 mg, 10 mg/40 mg oral tablets

How should I store amlodipine/olmesartan?

Amlodipine/olmesartan should be stored at room temperature, between 68 F to 77 F (20 C to 25 C). It can be exposed to temperatures between 59 F to 86 F (15 C to 30 C), for shorter periods of time, such as when transporting it. Store in a cool, dry place, tightly closed.

Side Effects

What are the most common side effects of amlodipine/olmesartan?

The most common side effect of amlodipine/olmesartan is listed below. Tell your healthcare provider if you have any of these side effects that bother you.

Swelling of the legs and ankles (edema)

There may be other side effects of amlodipine/olmesartan that are not listed here. Contact your healthcare provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088. In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.

What are the serious side effects of amlodipine/olmesartan?

While less common, the most serious side effects of amlodipine/olmesartan are described below, along with what to do if they happen.

Decreased Blood Pressure (Hypotension). Amlodipine/olmesartan may cause low blood pressure in people with low levels of fluids or salt. This can happen especially in people taking a medicine that causes you to pee more often (diuretic). If you feel faint or dizzy, lie down. Tell your healthcare provider right away if you have any of the following symptoms of low blood pressure.

Dizziness, feeling lightheaded, or fainting
Confusion
Feeling weak or tired

Chest Pain or Heart Attack. When you first start taking amlodipine/olmesartan or increase your dose, your chest pain (angina) may get worse or you may have a heart attack. This risk is higher if you have severe obstructive coronary artery disease, a condition where the blood vessels that deliver blood, oxygen, and nutrients to your heart get blocked. Call your healthcare provider immediately if you have any of the following symptoms of a heart attack.

Severe chest pain, which may feel like pressure, tightness, squeezing or aching
Discomfort that spreads to the shoulder, arm, back, neck, or jaw
Cold sweat
Unusual tiredness
Heartburn or indigestion
Lightheadedness or sudden dizziness

Kidney Damage. Kidney damage can happen when taking amlodipine/olmesartan. Call your healthcare provider right away if you have any of the following symptoms of kidney damage.

Reduced need to pee
Swelling in your feet, ankles, or legs
Weakness or unusual tiredness
Difficulty catching your breath or chest pain/pressure
Confusion
Nausea
Seizures

Diarrhea. Amlodipine/olmesartan may cause severe or persistent diarrhea. Call your healthcare provider right away if you have any of the following.

Severe diarrhea and weight loss
Diarrhea that does not go away
Diarrhea with weakness, dizziness, or fever

High Potassium Level (Hyperkalemia). Amlodipine/olmesartan can cause a high potassium level (hyperkalemia), which can be serious and may lead to death. Your healthcare provider may check your potassium levels, especially if you take certain other medicines. Call your healthcare provider right away if you have any of the following symptoms of a high potassium level.

Muscle weakness or unusual tiredness
Slow heartbeat or feeling of skipped heartbeats
Nausea or vomiting
Trouble breathing
Abnormal heart rhythm

Severe Allergic Reactions. Amlodipine/olmesartan may cause allergic reactions, which can be serious. Stop taking amlodipine/olmesartan and get help right away if you have any of the following symptoms of a serious allergic reaction.

Breathing problems or wheezing
Racing heart
Fever or general ill feeling
Swollen lymph nodes
Swelling of the face, lips, mouth, tongue, or throat
Trouble swallowing or throat tightness
Itching, skin rash, or pale red bumps on the skin called hives
Nausea or vomiting
Dizziness, feeling lightheaded, or fainting
Stomach cramps
Joint pain

Warnings & Precautions

Who should not use amlodipine/olmesartan?

Allergies to Ingredients. People who are allergic to any of the following should not take amlodipine/olmesartan.

Azor
Amlodipine
Olmesartan
Any of the ingredients in the specific product dispensed

Your pharmacist can tell you all of the ingredients in the specific amlodipine/olmesartan products they stock.

Drug Interactions. Amlodipine/olmesartan should not be taken while you are using certain other medicines. Before taking amlodipine/olmesartan, tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. See the Interactions section for more details.

What should I know about amlodipine/olmesartan before using it?

Do not take amlodipine/olmesartan unless it has been prescribed to you by a healthcare provider. Take it as prescribed.

Do not share amlodipine/olmesartan with other people, even if they have the same condition as you. It may harm them.

Keep amlodipine/olmesartan out of the reach of children.

Amlodipine/olmesartan can affect your alertness or coordination. Do not drive or do other activities that require alertness or coordination until you know how amlodipine/olmesartan affects you.

What should I tell my healthcare provider before using amlodipine/olmesartan?

Tell your healthcare provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if amlodipine/olmesartan is right for you.

In particular, make sure that you discuss any of the following.

Current and Past Health Conditions. Tell your healthcare provider if you have any of the following.

Heart problems
Liver problems
Kidney problems
Diabetes
Imbalanced electrolytes
Persistent or severe vomiting or diarrhea

Pregnancy. Amlodipine/olmesartan may cause harm to an unborn baby. Tell your healthcare provider if you are or plan to become pregnant. If you become pregnant, stop taking amlodipine/olmesartan right away and contact your healthcare provider.

Breastfeeding. Amlodipine/olmesartan passes into breast milk. Tell your healthcare provider if you are breastfeeding or plan to breastfeed. Your healthcare provider will advise you if you should take amlodipine/olmesartan while breastfeeding.

Interactions

Does amlodipine/olmesartan interact with foods or drinks?

There are no known interactions between amlodipine/olmesartan and foods or drinks.

It is unknown if drinking alcohol will affect amlodipine/olmesartan. The risk of dizziness may be increased if you drink alcohol while taking amlodipine/olmesartan.

Does amlodipine/olmesartan interact with other medicines (drug interactions)?

Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.

In particular, make sure that you discuss if you are using any of the following before taking amlodipine/olmesartan.

Simvastatin, which is a medicine to lower cholesterol
Cyclosporine (Gengraf, Neoral, Sandimmune, and others) or tacrolimus (Prograf, Astagraf, and others), which is a medicine to suppress your immune system
A nonsteroidal anti-inflammatory drug (NSAID), such as ibuprofen, naproxen, and others, which are contained in many prescription and OTC products for pain, swelling, and fever
Aliskiren (Tekturna), which is a medicine for high blood pressure
An angiotensin-converting enzyme (ACE) inhibitor, which is a medicine for high blood pressure, heart failure, and certain kidney problems
An angiotensin II receptor blocker (ARB), which is a medicine for high blood pressure, heart failure, and other heart conditions
A diuretic, also called a water pill, which is a medicine used to reduce edema (fluid retention) and blood pressure
A supplement or salt-substitute containing potassium
Colesevelam (Welchol), which is a medicine for high cholesterol and high blood sugar from type 2 diabetes
Lithium, which is a medicine for certain mental health conditions
Diltiazem (Cardizem CD and others), which is a medicine used for high blood pressure and other conditions
Any medicine for high blood pressure

Some other medicines may alter the blood levels of amlodipine/olmesartan, and vice versa. Tell your healthcare provider about all medicines that you take or have recently taken.

This may not be a complete list of medicines that can interact with amlodipine/olmesartan. Always check with your healthcare provider.

Does Amlodipine/Olmesartan (Azor) interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose/Missed Dose

What should I do if I accidentally use too much amlodipine/olmesartan?

If you or someone else has used too much amlodipine/olmesartan, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.

What should I do if I miss a dose of amlodipine/olmesartan?

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and only take the next dose. Do not take double or extra doses.