Uses

This medication is used to treat or prevent serious blood cell disorders (such as thrombocytopenia, neutropenia, anemia) caused by certain drugs (folic acid antagonists such as methotrexate, trimethoprim, pyrimethamine).

How to use Leucovorin Calcium

Take this medication by mouth with or without food as directed by your doctor, usually every 6 hours or once daily.

The dosage is based on your medical condition and response to treatment.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

Tell your doctor if you are unable to take this medication because of nausea/vomiting. You may need to be switched to the injection form of this medication.

Side Effects

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking leucovorin, tell your doctor or pharmacist if you are allergic to it; or to levoleucovorin; or to folic acid or folinic acid; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: certain anemias (due to vitamin B12 deficiency).

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Consult your doctor before breastfeeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Leucovorin is very similar to levoleucovorin. Do not use medications containing levoleucovorin while using leucovorin.

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Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call 1-800-222-1222. Canada residents can call 1-844-764-7669.

Notes Notes

Do not share this medication with others.

Lab and/or medical tests (such as kidney function, complete blood count, folic acid antagonist blood levels) should be done while you are taking this medication. Keep all medical and lab appointments. Consult your doctor for more details.

Missed Dose Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Storage Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Images

leucovorin calcium 15 mg tablet

leucovorin calcium 15 mg tablet

Color: whiteShape: roundImprint: LP 186

This medicine is a white, round, scored, tablet imprinted with "LP 186".

leucovorin calcium 10 mg tablet

leucovorin calcium 10 mg tablet

Color: whiteShape: roundImprint: LP 185

This medicine is a white, round, scored, tablet imprinted with "LP 186".

leucovorin calcium 5 mg tablet

leucovorin calcium 5 mg tablet

Color: whiteShape: roundImprint: LP 184

This medicine is a white, round, scored, tablet imprinted with "LP 186".

leucovorin calcium 25 mg tablet

leucovorin calcium 25 mg tablet

Color: pale greenShape: roundImprint: b 485

This medicine is a white, round, scored, tablet imprinted with "LP 186".

leucovorin calcium 25 mg tablet

leucovorin calcium 25 mg tablet

Color: peachShape: roundImprint: ING 184

This medicine is a white, round, scored, tablet imprinted with "LP 186".

leucovorin calcium 10 mg tablet

leucovorin calcium 10 mg tablet

Color: off-whiteShape: roundImprint: 54 942

This medicine is a white, round, scored, tablet imprinted with "LP 186".

leucovorin calcium 25 mg tablet

leucovorin calcium 25 mg tablet

Color: yellowShape: roundImprint: 54 013

This medicine is a white, round, scored, tablet imprinted with "LP 186".

leucovorin calcium 5 mg tablet

leucovorin calcium 5 mg tablet

Color: off-whiteShape: roundImprint: 54 293

This medicine is a white, round, scored, tablet imprinted with "LP 186".

leucovorin calcium 10 mg tablet

leucovorin calcium 10 mg tablet

Color: whiteShape: roundImprint: ING 182

This medicine is a white, round, scored, tablet imprinted with "LP 186".

leucovorin calcium 5 mg tablet

leucovorin calcium 5 mg tablet

Color: whiteShape: roundImprint: ING 181

This medicine is a white, round, scored, tablet imprinted with "LP 186".

leucovorin calcium 5 mg tablet

leucovorin calcium 5 mg tablet

Color: whiteShape: roundImprint: b 484

This medicine is a white, round, scored, tablet imprinted with "LP 186".

leucovorin calcium 15 mg tablet

leucovorin calcium 15 mg tablet

Color: peachShape: roundImprint: ING 183

This medicine is a white, round, scored, tablet imprinted with "LP 186".

leucovorin calcium 15 mg tablet

leucovorin calcium 15 mg tablet

Color: yellowShape: roundImprint: 54 650

This medicine is a white, round, scored, tablet imprinted with "LP 186".

leucovorin calcium 5 mg tablet

leucovorin calcium 5 mg tablet

Color: off-whiteShape: roundImprint: logo and 358

This medicine is a white, round, scored, tablet imprinted with "LP 186".

Drug Survey

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.