Cholic Acid/Bile Salt Efflux Pump (BSEP) Inhibitors Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Your other medicine may change how your body processes cholic acid.

What might happen:

Your liver condition may worsen.

What you should do about this interaction:

Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking both of these medicines. Your doctor may want to check how your liver is working with blood tests. Be sure to keep all of your laboratory appointments. Let your doctor know right away if you have any signs of worsening liver impairment, such as yellowing of the whites of the eyes or skin, dark or brown (tea-colored) urine, pain on the right side of the stomach, bleeding or bruising that occurs more easily than normal, or increased lethargy.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Cholbam (cholic acid) US prescribing information. Manchester Pharmaceuticals, Inc. November 2, 2020..

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.