DUOPA Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • orthostatic hypotension, a form of low blood pressure
  • a feeling of restlessness with inability to sit still

If experienced, these tend to have a Less Severe expression i

  • constipation
  • difficulty sleeping
  • loss of muscle coordination
  • a type of abnormal movement disorder called dyskinesia
  • headache
  • nausea
  • vomiting
  • anxious feelings

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • involuntary eyelid twitching

If experienced, these tend to have a Less Severe expression i

  • confusion
  • a painful condition that affects the nerves in the legs and arms called peripheral neuropathy
  • blurred vision
  • dry mouth
  • indigestion
  • dizziness
  • low energy
  • muscle twitching
  • fluid retention in the legs, feet, arms or hands
  • temporary redness of face and neck
  • decreased appetite
  • diarrhea
  • abnormal color of urine
  • generalized weakness
  • abnormal dreams

RARE side effects

If experienced, these tend to have a Severe expression i

  • a type of blood disorder where the red blood cells burst called hemolytic anemia
  • anemia
  • decreased blood platelets
  • very low levels of granulocytes, a type of white blood cell
  • low levels of white blood cells
  • mental problems from taking the drug
  • suicidal behavior
  • suicidal thoughts
  • extrapyramidal disease, a type of movement disorder
  • increased pressure in the eye
  • high blood pressure
  • a heart attack
  • abnormal heart rhythm
  • an ulcer of the duodenum
  • priapism, a prolonged erection of the penis
  • inflammation of the skin with blisters
  • high amount of bilirubin in the blood
  • rapid deep breathing
  • abnormal liver function tests
  • accidental falls
  • an inability to control impulsive behavior
  • a high alanine transaminase level
  • a high aspartate transaminase level
  • painful and involuntary movement of the eyes called oculogyric crisis
  • IgA vasculitis

If experienced, these tend to have a Less Severe expression i

  • grinding of the teeth
  • an extreme sense of wellbeing called euphoria
  • double vision
  • a sore throat
  • excessive saliva production
  • irritation of the stomach or intestines
  • hair loss
  • drowsiness
  • memory loss
  • lockjaw
  • taste impairment
  • numbness
  • visible water retention
  • weight gain
  • weight loss
  • hoarseness
  • cough
  • hiccups
  • difficulty swallowing
  • gas
  • an inability to completely empty the bladder
  • involuntary leakage of urine
  • nervousness
  • inflammation of a vein
  • a feeling of general discomfort called malaise
  • intense abdominal pain
  • an increased interest in having sexual intercourse
  • leg pain
  • drug-induced hot flashes
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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.