If you are:
Not Recommended: FETAL MALFORMATIONS AND EMBRYOLETHALITY SEEN IN RATS/RABBITS AT LESS THAN MRHD.
Absolute Contraindication: POTENTIAL SERIOUS ADV EFFECTS ON INFANT; CONTRAINDICATED PER BRIGGS
An adult over 60:
management or monitoring precaution: General-Patients older than 70 years of age are at increased risk for myelosuppression.
Giving temozolomide to a child under 12:
management or monitoring precaution: No efficacy established in pediatric studies of brain stem glioma and astrocytoma.