Uses

What is Qbrexza used for?

Qbrexza (glycopyrronium) is commonly used to treat excessive sweating (hyperhidrosis) in the armpits. 

Qbrexza may also be used for other conditions as determined by your healthcare provider.

How does Qbrexza work (mechanism of action)?

Qbrexza works by preventing the stimulation of sweat glands. This lowers the amount of sweating, helping keep your armpits dry.

How is Qbrexza supplied (dosage forms)?

Brands and other names

  • Qbrexza

Dosage forms and strengths

  • 2.4% single-use cloths 

How should I store Qbrexza?

Qbrexza should be stored at room temperature, between 68 F to 77 F (20 C to 25 C). It can be exposed to temperatures between 59 F to 86 F (15 C to 30 C) for shorter periods of time, such as when transporting it. Store in a cool, dry place. Do not store near flames or fire.

Side Effects

What are the most common side effects of Qbrexza?

The most common side effects of Qbrexza are listed below. Tell your healthcare provider if you have any of these side effects that bother you.

  • Dry mouth, nose, throat, eyes, and skin 
  • Dilated pupils
  • Sore throat 
  • Headache
  • Problems peeing
  • Blurred vision (see below)
  • Constipation 
  • Redness, burning, stinging, and itching in the underarm area

There may be other side effects of Qbrexza that are not listed here. Contact your healthcare provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088. In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.

What are the serious side effects of Qbrexza?

While less common, the most serious side effects of Qbrexza are described below, along with what to do if they happen.

Severe Allergic Reactions. Qbrexza may cause allergic reactions, which can be serious. Stop using Qbrexza and get help right away if you have any of the following symptoms of a serious allergic reaction.

  • Breathing problems or wheezing
  • Racing heart
  • Fever or general ill feeling
  • Swollen lymph nodes
  • Swelling of the face, lips, mouth, tongue, or throat
  • Trouble swallowing or throat tightness
  • Itching, skin rash, or pale red bumps on the skin called hives
  • Nausea or vomiting
  • Dizziness, feeling lightheaded, or fainting
  • Stomach cramps
  • Joint pain

Inability to Empty Bladder (Urinary Retention). Qbrexza might make it harder to empty your bladder, especially if you already have a blockage. Stop using Qbrexza and call your healthcare provider right away if you are having trouble peeing or cannot empty your bladder.

Body Temperature Regulation. Qbrexza can affect your ability to regulate your body temperature. This could make you become very hot, especially in hot weather or after exercising a lot. You should drink water and avoid overheating and dehydration. Call your healthcare provider right away if you are severely ill and have the following symptoms.

  • Excessive or no sweating
  • Dry mouth
  • Feeling very hot
  • Feeling thirsty
  • Not able to pee

Blurred Vision. Qbrexza might cause your vision to become blurry. If this happens, stop using Qbrexza and call your healthcare provider right away. Avoid driving, operating heavy machinery, or performing hazardous work until your vision becomes normal again. 

Warnings & Precautions

Who should not use Qbrexza?

Allergies to Ingredients. People who are allergic to any of the following should not use Qbrexza.

  • Qbrexza
  • Glycopyrronium
  • Any of the ingredients in the specific product dispensed

Your pharmacist can tell you all of the ingredients in Qbrexza.

Glaucoma. Glaucoma is a condition that may lead to trouble seeing or blindness because of damage to the optic nerve in your eye. Qbrexza can make this condition worse.

Slowed Gut Movement. Paralytic ileus is a type of ileus where your intestines are unable to move food through them. Qbrexza can make this condition worse. 

Severe Ulcerative Colitis. Ulcerative colitis is an inflammatory bowel disease that can cause pain and sores in the lining of your large intestine. Qbrexza can make this condition worse.

Toxic Megacolon. Toxic megacolon is a rare and serious condition that can cause your colon to swell, weaken, and stop working properly. Qbrexza can make this condition worse. 

Myasthenia gravis. Myasthenia gravis is a condition that can cause muscle weakness. Qbrexza can make this condition worse. It should not be used if you have a history of this condition.

Sjögren’s syndrome. Sjögren’s syndrome is a condition that leads to dry eyes and dry mouth because your body does not make enough tears and saliva. Qbrexza can make this condition worse. 

What should I know about Qbrexza before using it?

Do not use Qbrexza unless it has been prescribed to you by a healthcare provider. Use it as prescribed.

Do not share Qbrexza with other people, even if they have the same condition as you. It may harm them.

Keep Qbrexza out of the reach of children.

Qbrexza is for use on the skin only. It should only be applied to clean, dry, intact skin in the underarm area.       

After wiping each armpit with a Qbrexza cloth, throw the cloth away in regular household trash out of the reach of children, pets, and others. Each Qbrexza cloth is good for one use and should not be reused.

Wash your hands with soap and water right away after applying Qbrexza and throwing away the cloth. If Qbrexza gets on your hands and you touch your eyes after using it, Qbrexza can cause your vision to get blurry. Do not drive, operate machinery, or do hazardous work until your vision returns to normal.  

Do not cover the treated area with a plastic bandage or dressing. This can cause too much medicine to be absorbed into your body, which increases your chance of having side effects.

Avoid fire or flames, including smoking, during and right after applying Qbrexza to your skin. Qbrexza is flammable. 

What should I tell my healthcare provider before using Qbrexza?

Tell your healthcare provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if Qbrexza is right for you.

In particular, make sure that you discuss any of the following.

Other Current and Past Health Conditions. Tell your healthcare provider if you have any of the following.

  • Prostate or bladder problems 
  • Trouble passing urine
  • Kidney problems

Other Medicines and Supplements. Qbrexza may interact with other medicines and supplements. Before using Qbrexza, tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. See the Interactions section for more details.

Pregnancy. It is not known if or how Qbrexza could affect pregnancy or harm an unborn baby. Tell your healthcare provider if you are or plan to become pregnant.

Breastfeeding. It is not known if Qbrexza passes into breast milk. Tell your healthcare provider if you are breastfeeding or plan to breastfeed. Your healthcare provider will advise you if you should use Qbrexza while breastfeeding.

How can I get more information about Qbrexza?

For more information about Qbrexza, you can visit the manufacturer’s website at getqbrexza.com or call them at 855-531-1859.

Interactions

Does Qbrexza interact with foods or drinks?

There are no known interactions between Qbrexza and foods or drinks.

It is unknown if drinking alcohol will affect Qbrexza.

Does Qbrexza interact with other medicines (drug interactions)?

Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.

In particular, make sure that you discuss if you are taking any other anticholinergic medicine, which includes antihistamines and certain medicines for overactive bladder, Parkinson’s disease, stomach problems, motion sickness, and others.

Some other medicines may alter the blood levels of Qbrexza. Tell your healthcare provider about all medicines that you take or have recently taken.

This may not be a complete list of medicines that can interact with Qbrexza. Always check with your healthcare provider.

Does Qbrexza (glycopyrronium) interact with other drugs you are taking?
Enter your medication into the WebMD interaction checker

Overdose/Missed Dose

What should I do if I accidentally use too much Qbrexza?

If you or someone else has used too much Qbrexza, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.

What should I do if I miss a dose of Qbrexza?

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and only apply the next dose. Do not apply double or extra doses.