Warnings:

This medication can commonly cause serious (even fatal) injection reactions. To decrease your risk, you may also be given other medications before each dose (such as an antihistamine, corticosteroid, H2 blocker, and acetaminophen). A health care professional will carefully monitor you during and for at least 2 hours after your infusion. Get medical help right away if you develop any signs of an infusion reaction, such as rash, flushing, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing, wheezing, chest discomfort/pain. Your infusion may be slowed down or stopped depending on your symptoms.

Naxitamab can cause serious nervous system problems. Pain is common and can be severe. Tell your doctor right away if you have pain in the abdomen, bones, neck, legs, or arms. Your doctor should prescribe medications to help prevent and relieve pain before and during treatment with this medication.

Rarely, this medication may cause a condition called reversible posterior leukoencephalopathy syndrome-RPLS, also known as posterior reversible encephalopathy syndrome-PRES. Get medical help right away if you develop headache that doesn't go away, seizures, sudden vision changes, mental/mood changes (such as confusion).

Warnings:

This medication can commonly cause serious (even fatal) injection reactions. To decrease your risk, you may also be given other medications before each dose (such as an antihistamine, corticosteroid, H2 blocker, and acetaminophen). A health care professional will carefully monitor you during and for at least 2 hours after your infusion. Get medical help right away if you develop any signs of an infusion reaction, such as rash, flushing, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing, wheezing, chest discomfort/pain. Your infusion may be slowed down or stopped depending on your symptoms.

Naxitamab can cause serious nervous system problems. Pain is common and can be severe. Tell your doctor right away if you have pain in the abdomen, bones, neck, legs, or arms. Your doctor should prescribe medications to help prevent and relieve pain before and during treatment with this medication.

Rarely, this medication may cause a condition called reversible posterior leukoencephalopathy syndrome-RPLS, also known as posterior reversible encephalopathy syndrome-PRES. Get medical help right away if you develop headache that doesn't go away, seizures, sudden vision changes, mental/mood changes (such as confusion).

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Uses

This medication is used to treat a certain type of cancer (neuroblastoma in bone or bone marrow). Naxitamab belongs to a class of drugs known as monoclonal antibodies. It works by slowing or stopping the growth of cancer cells.

How to use

Read the Patient Information Leaflet if available from your pharmacist before you start using naxitamab and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

This medication is given by injection into a vein as directed by your doctor, usually on days 1, 3, and 5 of each treatment cycle. A treatment cycle is usually every 4 or every 8 weeks. The injection is given by a health care professional, usually over 30 to 60 minutes. Your doctor should prescribe other medications for you to take before and during treatment to help lessen the risk of side effects such as pain, infusion reactions, and nausea or vomiting. Carefully follow your doctor's directions for all your medications.

The dosage and treatment schedule are based on your medical condition, weight, and response to treatment.

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.