This medication is used to treat Alzheimer's disease. It is thought to work by decreasing a certain substance (amyloid beta) that builds up in the brain of people with Alzheimer's disease. Aducanumab belongs to a class of drugs known as monoclonal antibodies. This medication is not a cure for Alzheimer's disease. It may help slow down worsening of this disease and may delay disability.
How to use Aducanumab-Avwa 100 Mg/Ml Intravenous Solution
This medication is given by injection into a vein as directed by your doctor, usually every 4 weeks. The injection is given by a health care professional, usually over 1 hour. The dosage is based on your medical condition, weight, and response to treatment. To reduce your risk of side effects, your doctor may start this medication at a low dose and gradually increase your dose.
Use this medication regularly to get the most benefit from it. To help you remember, it may help to mark your calendar with a reminder.
See also Warning section.
Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
This medication may increase your risk of serious (possibly fatal) side effects such as temporary swelling of the brain, or small spots of bleeding in or on the surface of the brain. These side effects are also known as amyloid-related imaging abnormalities (ARIA). Your doctor may order a genetic test to measure your risk for ARIA before you start this medication. If the genetic test shows you are at greater risk, your doctor should discuss with you the risks and benefits of starting aducanumab. Your doctor will do magnetic resonance imaging (MRI) scans before and during treatment to check for these side effects. If you are also taking medications that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, NSAIDs such as ibuprofen/naproxen, "blood thinners" such as warfarin/dabigatran), your doctor will monitor you more closely for bleeding. ARIA usually go away over time. They do not always cause symptoms, but tell your doctor right away if you develop symptoms such as headache, dizziness, nausea, confusion, seizures, trouble walking, or vision changes.
Before using aducanumab, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history.
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.
See also Warning section.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
Not applicable. This medication is given in a hospital or clinic and will not be stored at home.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.