This product contains 2 ingredients: mineral oil and dimethicone. It is used to treat head lice, tiny insects that infest and irritate your scalp. Head lice lay small white eggs (nits) at the roots of hair close to the scalp, especially on the hairline at the back of the neck and behind the ears. Mineral oil and dimethicone work by stopping the lice and their eggs from getting air, killing them by suffocation.

How to use Nix Ultra Topical Solution Scabicides And Pediculocides

Read and follow all directions on the product package before using this medication. If you have any questions, consult your pharmacist.

People who are in close contact with the infected person, such as members of the same household, should also be checked for lice and nits. Use a comb to help look for head lice or nits. Treat everyone infected with lice on the same day to prevent getting lice again. A regular comb can be used before treatment to remove any tangles. Clean the comb thoroughly after use. See also Notes section.

This medication is for external use on the scalp only (not for pubic lice). Do not use on scalp that is very irritated or injured. Use this medication when your hair is dry. Do not wet your hair before applying. Avoid contact with your eyes. Protect your eyes with a washcloth or towel during application. Close your eyes tightly during application and avoid getting this product in your eyes, nose, or mouth. If the medication accidentally gets into the eye(s), rinse right away with plenty of water. Since you should keep your eyes closed during application, you may need to have another person help you apply this medication. Children will need an adult to apply this medication for them. Apply this medication carefully over all hair on the scalp as directed by the manufacturer. Be sure to completely wet the hair and scalp, behind the ears, and the back of the neck.

After application, leave the medication on the hair for 10 minutes. Do not leave on longer than directed. Do not cover the treated hair (such as with a cap or wrapped foil). After 10 minutes, wash hair thoroughly with regular shampoo. Do not use conditioner. Do not use shampoo that contains conditioner. Towel dry hair.

Use a lice comb to carefully comb hair and remove the dead lice and nits. Follow the manufacturer's directions to divide hair into sections and comb through one section at a time. Clean the comb during use by wiping lice and nits onto a clean tissue or dry paper towel. Place the used tissue or paper towel into a sealable plastic bag to throw away later. After combing, recheck the hair for lice or nits. Soak the lice removal comb in hot water for 10 minutes. Inspect the comb before using it again.

You or anyone who helps you apply this medication should wash hands after application. Check hair after 7 days. If lice or nits are present, repeat treatment with this product. Tell your doctor if head lice remain after the second treatment with this product.

Side Effects

Skin or eye irritation/redness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

If your doctor has directed you to use this product, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this product do not have serious side effects.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.


Before using this product, tell your doctor or pharmacist if you are allergic to mineral oil or dimethicone; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: skin conditions or sensitivities.

Constant or forceful scratching of the skin/scalp may lead to a bacterial skin infection. Tell your doctor right away if you develop pus or worsening redness.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

This product is flammable. Do not use near an open flame or heat source which uses an open flame.

Tell your doctor if you are pregnant before using this medication.

It is unknown if this product passes into breast milk. Consult your doctor before breast-feeding.


Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

This product may react with certain hair care and hair tinting products.

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This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.


To avoid spreading lice to another person or getting lice again, machine-wash all head wear, clothing, bed linens, and towels with hot water, then dry in a dryer at high setting for at least 20 minutes. Items such as pillows or stuffed animals that cannot be washed should be dry cleaned, sealed in a plastic bag for at least 2 weeks, or sprayed with a disinfectant that kills lice. Brushes or combs should be soaked in hot water (hotter than 130 degrees F/54 degrees C) for at least 5 to 10 minutes. Furniture and floors should be thoroughly vacuumed.

Missed Dose

Not applicable.


This product is flammable. Store at room temperature away from heat, open flame, or moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.


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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.