How to use Tivdak 40 Mg Intravenous Solution Antineoplas-Tissue Factor Directed Ab-Microtub Disrupt Conj
See also Warning section.
This medication is given by injection into a vein by a health care professional as directed by your doctor, usually once every 3 weeks. The medication is given over 30 minutes.
The dosage is based on your medical condition, weight, and response to treatment.
Use this medication regularly to get the most benefit from it. It may help to mark your calendar when to receive each dose.
See also Warning section.
Nosebleeds, constipation, diarrhea, nausea, vomiting, loss of appetite, stomach/abdominal pain, weight loss, tiredness, or muscle/joint pain may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
People using this medication may have serious side effects. However, you have been prescribed this drug because your doctor has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may decrease your risk.
Tell your doctor right away if you have any serious side effects, including: easy bruising/bleeding, signs of infection (such as chills, fever, swollen lymph nodes), sores/ulcers in the mouth/nose/genital area, bloody urine, unusual vaginal bleeding, black/tarry stools, numbness/tingling of arms/legs, muscle weakness.
Get medical help right away if you have any very serious side effects, including: signs of lung problems (such as cough that doesn't go away, chest pain, shortness of breath), weakness on one side of the body, confusion.
Tisotumab vedotin can commonly cause a rash that is usually not serious. However, you may not be able to tell it apart from a rare rash that could be a sign of a severe reaction. Get medical help right away if you develop any rash.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Tisotumab vedotin may cause serious eye problems. You should have regular eye exams before and during treatment with this medication. Follow your doctor's instructions carefully on what eye drops to use before and after your infusion of this medication. Do not wear contact lenses while you are on treatment with this medication unless directed by the doctor. Tell your doctor right away if you have signs of eye problems, including dry eyes, eye pain/redness/irritation, or blurred/decreased vision. Ask your doctor or pharmacist for more details.
Before receiving tisotumab vedotin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
To lower the chance of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and avoid activities such as contact sports.
Older adults may be more sensitive to the side effects of this drug.
Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while using tisotumab vedotin. Tisotumab vedotin may harm an unborn baby. Your doctor should order a pregnancy test before you start this medication. Women using this medication should ask about reliable forms of birth control during treatment and for 2 months after the last dose. Men using this medication should ask about reliable forms of birth control during treatment and for 4 months after the last dose. If you or your partner becomes pregnant, talk to your doctor right away about the risks and benefits of this medication.
It is unknown if this drug passes into breast milk. Because of the possible risk to the infant, breast-feeding is not recommended while using this drug and for 3 weeks after the last dose. Consult your doctor before breast-feeding.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
Not applicable. This medication is given in a hospital or clinic or doctor's office and will not be stored at home.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.