TRAMADOL HCL-ACETAMINOPHEN Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

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If experienced, these tend to have a Less Severe expression i

  • dry mouth
  • constipation
  • sensation of spinning or whirling
  • dizziness
  • difficulty sleeping
  • temporary redness of face and neck
  • headache
  • nausea
  • vomiting
  • INFREQUENT side effects

    If experienced, these tend to have a Severe expression i

  • abnormal liver function tests
  • decreased lung function
  • If experienced, these tend to have a Less Severe expression i

  • confusion
  • blurred vision
  • high blood pressure
  • widening of blood vessels
  • indigestion
  • joint pain
  • drowsiness
  • excessive sweating
  • a skin rash
  • decreased appetite
  • gas
  • diarrhea
  • nervousness
  • generalized weakness
  • intense abdominal pain
  • anxious feelings
  • RARE side effects

    If experienced, these tend to have a Severe expression i

  • decreased blood platelets
  • very low levels of granulocytes, a type of white blood cell
  • low levels of white blood cells
  • low levels of a type of white blood cell called neutrophils
  • vocal cord swelling
  • acute liver failure
  • damage to the liver and inflammation
  • inflammation of the skin due to an allergy
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • a type of allergic reaction called angioedema
  • a type of bumpy skin rash called a maculopapular rash
  • a type of skin disorder called acute generalized exanthematous pustulosis
  • low blood sugar
  • a disorder with excess antidiuretic hormone called syndrome of inappropriate antidiuretic hormone
  • decreased function of the adrenal gland
  • deficiency of a substance that promotes masculinization
  • low amount of sodium in the blood
  • anemia
  • suicidal behavior
  • addiction to a drug
  • serotonin syndrome, a type of disorder with high serotonin levels
  • hearing loss
  • a low supply of oxygen rich blood to the heart
  • a clot in the lung
  • abnormal heart electrical signals
  • prolonged QT interval on EKG
  • inadequate blood flow in the extremities
  • fluid in the lungs
  • bronchospasm
  • liver failure
  • inflammation of the liver called hepatitis
  • seizures
  • sleep apnea
  • trouble breathing
  • an increased need to urinate often
  • a significant type of allergic reaction called anaphylaxis
  • accidental falls
  • an accidental injury
  • fast heartbeat
  • If experienced, these tend to have a Less Severe expression i

  • erythema or redness of skin or mucous membrane
  • hives
  • a skin rash
  • mood changes
  • agitation
  • an extreme sense of wellbeing called euphoria
  • depression
  • a change in vision
  • decreased pupil size
  • ringing in the ears
  • bruising under the skin
  • throat irritation
  • inflammation of the tissue lining the sinuses
  • stomatitis, a condition with painful swelling and sores inside the mouth
  • inflammation of the lining of the stomach and intestines
  • urinary tract infection
  • bloody urine
  • the inability to have an erection
  • a problem with menstrual periods
  • neck stiffness
  • an abnormal increase in muscle tone
  • muscle pain
  • leg cramps
  • delirium
  • fainting
  • a sleep disorder
  • fever
  • flu-like symptoms
  • chills
  • muscle twitching
  • taste impairment
  • fluid retention in the legs, feet, arms or hands
  • weight loss
  • heart throbbing or pounding
  • yawning
  • difficult or painful urination
  • high blood sugar
  • bruising
  • indifferent behavior
  • abnormal dreams
  • night sweats
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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.