Phenytoin/Fluvastatin Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Fluvastatin may slow down how quickly your body processes phenytoin.

What might happen:

The blood levels of your seizure medicine may increase and cause toxic effects. You may experience slurred speech, increased confusion, nausea, unsteadiness walking, weakness, fatigue, or dizziness.

What you should do about this interaction:

Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Lescol (fluvastatin sodium) US prescribing information. Novartis Pharmaceuticals Corporation October, 2012.
  • 2.US Food and Drug Administration (FDA). Drug Development and Drug Interactions: Table of Substrates, Inhibitors and Inducers. Available at: http://www.fda.gov/Drugs/DevelopmentApprovalProcess/DevelopmentResources/D rugInteractionsLabeling/ucm093664.htm. Updated 08/05/2011.