Hydralazine-hydrochlorothiazide Oral Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • low amount of sodium in the blood
  • low amount of potassium in the blood
  • low blood pressure
  • acid base problem with low chloride and basic pH blood
  • If experienced, these tend to have a Less Severe expression i

  • decreased appetite
  • headache
  • heart throbbing or pounding
  • nausea
  • vomiting
  • diarrhea
  • fast heartbeat
  • INFREQUENT side effects

    If experienced, these tend to have a Severe expression i

  • low amount of magnesium in the blood
  • damage to the kidneys
  • decreased kidney function
  • high blood sugar
  • a painful condition that affects the nerves in the legs and arms called peripheral neuropathy
  • angina, a type of chest pain
  • itching
  • hives
  • a condition with symptoms that resemble lupus
  • a skin rash
  • visible water retention
  • If experienced, these tend to have a Less Severe expression i

  • abnormal sexual function
  • orthostatic hypotension, a form of low blood pressure
  • dizziness
  • low energy
  • decreased appetite
  • nausea
  • vomiting
  • diarrhea
  • stomach cramps
  • excessive watery eyes
  • low blood pressure
  • stuffy nose
  • constipation
  • temporary redness of face and neck
  • trouble breathing
  • RARE side effects

    If experienced, these tend to have a Severe expression i

  • increased activity of the parathyroid gland
  • a type of joint disorder due to excess uric acid in the blood called gout
  • high amount of calcium in the blood
  • a type of blood disorder where the red blood cells burst called hemolytic anemia
  • low blood counts due to bone marrow failure
  • large purple or brown skin blotches
  • decreased blood platelets
  • very low levels of granulocytes, a type of white blood cell
  • low levels of white blood cells
  • nearsightedness
  • allergic reaction causing inflammation of blood vessels
  • inflammation of the blood vessels
  • a type of inflammation of the lung called interstitial pneumonitis
  • acute respiratory distress syndrome, a type of lung disorder
  • inflammation of the liver called hepatitis
  • a blockage of the bile duct that resulting in high bilirubin levels
  • acute inflammation of the pancreas
  • a type of kidney inflammation called interstitial nephritis
  • erythema multiforme, a type of allergic skin reaction
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • skin rash with sloughing
  • systemic lupus erythematosus, an autoimmune disease
  • high amount of uric acid in the blood
  • a significant type of allergic reaction called anaphylaxis
  • secondary angle-closure glaucoma, a type of eye disorder
  • a yellowing of the eyes or skin from buildup of bilirubin called jaundice
  • cancer of the squamous cells in the skin
  • choroidal effusion
  • anemia
  • increased eosinophils in the blood
  • paralysis of the intestines
  • glomerulonephritis, a condition that affects the kidneys
  • swollen lymph nodes
  • an enlarged spleen
  • If experienced, these tend to have a Less Severe expression i

  • high cholesterol
  • high amount of triglyceride in the blood
  • blurred vision
  • inflammation of the salivary glands
  • irritation of the stomach or intestines
  • constipation
  • the inability to have an erection
  • muscle spasm
  • sensation of spinning or whirling
  • fever
  • headache
  • nervousness
  • a feeling of pins and needles on skin
  • generalized weakness
  • confusion
  • depression
  • pink eye
  • joint pain
  • chills
  • muscle tremors
  • difficult or painful urination
  • poisoning caused by anticholinergic medication
  • anxious feelings
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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.