Rosuvastatin/Aluminum Hydroxide; Magnesium Hydroxide Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Taking these medicines at the same time may decrease how much rosuvastatin your body absorbs.

What might happen:

Your may notice your cholesterol levels increase.

What you should do about this interaction:

Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. If you need to take an antacid containing aluminum hydroxide and/or magnesium hydroxide, try to take it at least two hours after you take your rosuvastatin.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Martin PD, Schneck DW, Dane AL, Warwick MJ. The effect of a combination antacid preparation containing aluminium hydroxide and magnesium hydroxide on rosuvastatin pharmacokinetics. Curr Med Res Opin 2008 Apr;24(4):1231-5.
  • 2.Crestor (rosuvastatin calcium) US prescribing information. AstraZeneca Pharmaceuticals LP May, 2016.