Does Emend Interact with other Medications?

Severe Interactions

These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • MODERATE CYP3A4 INHIBITORS/LUMATEPERONE (>21 MG)
  • MODERATE CYP3A4 INHIBITORS/MITAPIVAT (> 20 MG)
  • STRONG AND MODERATE CYP3A4 INHIBITORS/LONAFARNIB
  • SLT STRONG & MODERATE CYP3A4 INHIBITORS/CILOSTAZOL (>50MG)
  • STRONG AND MODERATE CYP3A4 INHIBITORS/ASUNAPREVIR
  • STRONG OR MODERATE CYP3A4 INHIBITORS/LOMITAPIDE
  • MODERATE CYP3A4 INHIBITORS/NALOXEGOL (> 12.5 MG)
  • MODERATE CYP3A4 INHIBITORS/RANOLAZINE (> 500 MG BID)
  • MODERATE CYP3A4 INHIBITORS/AVANAFIL (> 50 MG)
  • STRONG OR MODERATE CYP3A4 INHIBITORS/FLIBANSERIN
  • APREPITANT; NETUPITANT/LURASIDONE (> 80 MG)
  • APREPITANT/CISAPRIDE
  • APREPITANT/ASTEMIZOLE; TERFENADINE
  • APREPITANT/PIMOZIDE
  • SELECTED CYP3A4 INHIBITORS/VARDENAFIL (> 5 MG)
  • Serious Interactions

    These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • SLT SENSITIVE 3A4 SUBSTRATES THAT INHIBIT 3A4/ORAL LEFAMULIN
  • APREPITANT; NETUPITANT/SELECTED STRONG CYP3A4 INDUCERS
  • APREPITANT; NETUPITANT/CARBAMAZEPINE
  • MODERATE CYP3A4 INHIBITORS/MAVACAMTEN
  • MODERATE CYP3A4 INHIBITORS/PACRITINIB
  • MODERATE CYP3A4 INHIBITORS/MOBOCERTINIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/FEXINIDAZOLE
  • MYELOSUPPRESSIVES; IMMUNOMODULATORS/SODIUM IODIDE I 131
  • STRONG AND MODERATE CYP3A4 INHIBITORS/INFIGRATINIB
  • SELECTED MODERATE CYP3A4 INHIBITORS/ALPRAZOLAM
  • MODERATE CYP3A4 INHIBITORS/VOCLOSPORIN
  • STRONG AND MODERATE CYP3A4 INHIBITORS/LURBINECTEDIN
  • MODERATE CYP3A4 INHIBITORS/SELPERCATINIB
  • MODERATE CYP3A4 INHIBITORS/PEXIDARTINIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/PEMIGATINIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/SELUMETINIB
  • MODERATE CYP3A4 INHIBITORS/TAZEMETOSTAT
  • STRONG AND MODERATE CYP3A4 INHIBITORS/LEMBOREXANT
  • MODERATE CYP3A4 INHIBITORS/ELEXACAFTOR-TEZACAFTOR-IVACAFTOR
  • MODERATE CYP3A4 INHIBITORS/ENTRECTINIB
  • SELECTED MODERATE CYP2C9 INDUCERS/SIPONIMOD
  • MODERATE CYP3A4 INHIBITORS/BRIGATINIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/ENCORAFENIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/TEZACAFTOR-IVACAFTOR
  • STRONG AND MODERATE CYP3A4 INHIBITORS/DEFLAZACORT
  • MODERATE CYP3A4 INHIBITORS/VENETOCLAX
  • MODERATE CYP3A4 INHIBITORS/NALOXEGOL (<= 12.5 MG)
  • MODERATE CYP3A4 INHIBITORS/COBIMETINIB; OLAPARIB; SONIDEGIB
  • STRONG & MODERATE CYP3A4 INHIBITORS/ELIGLUSTAT
  • MODERATE CYP3A4 INHIBITORS/SUVOREXANT (> 10 MG)
  • MODERATE CYP3A4 INHIBITORS/ERGOT ALKALOIDS
  • STRONG & MODERATE CYP3A4 INHIBITORS/GUANFACINE
  • STRONG OR MODERATE CYP3A4 INHIBITORS/SIMEPREVIR
  • STRONG AND MODERATE CYP3A4 INHIBITORS/BOSENTAN
  • SELECTED MYELOSUPPRESSIVE AGENTS/CLOZAPINE
  • MODERATE CYP3A4 INHIBITORS/BOSUTINIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/IVACAFTOR
  • SELECTED MYELOSUPPRESSIVE AGENTS/DEFERIPRONE
  • MODERATE CYP3A4 INHIBITORS/COLCHICINE
  • MODERATE CYP3A4 INHIBITORS/TOLVAPTAN
  • MODERATE CYP3A4 INHIBITORS/IVABRADINE
  • APREPITANT/WARFARIN
  • APREPITANT/STEROIDAL CONTRACEPTIVES
  • SELECTED MODERATE CYP3A4 INHIBITORS/EPLERENONE
  • Moderate Interactions

    These medications may cause some risk when taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • SELECTED SENSITIVE CYP3A4 SUBSTRATES/SCHISANDRA
  • MODERATE CYP3A4 INHIBITORS/LUMATEPERONE (<=21 MG)
  • MODERATE CYP3A4 INHIBITORS/MITAPIVAT (<= 20 MG)
  • MODERATE CYP3A4 INHIBITORS/DARIDOREXANT
  • SLT MODERATE AND WEAK CYP3A4 INHIBIT/SIROLIMUS PROTEIN-BOUND
  • MODERATE CYP3A4 INHIBITORS/RIMEGEPANT
  • MODERATE CYP3A4 INHIBITORS/AVAPRITINIB
  • MODERATE CYP3A4 INHIBITORS/UBROGEPANT
  • MODERATE AND WEAK CYP3A4 INHIBITORS/TACROLIMUS
  • MODERATE CYP3A4 INHIBITORS/ZANUBRUTINIB
  • MODERATE CYP3A4 INHIBITORS/ABEMACICLIB
  • SELECTED MODERATE CYP3A4 INHIBITORS/IVOSIDENIB
  • MODERATE CYP3A4 INHIBITORS/CABERGOLINE
  • SELECTED MODERATE CYP3A4 INHIBITORS/ACALABRUTINIB
  • MODERATE CYP3A4 INHIBITORS/QUETIAPINE
  • MODERATE CYP3A4 INHIBITORS/BROMOCRIPTINE
  • MODERATE CYP3A4 INHIBITORS/BREXPIPRAZOLE
  • MODERATE CYP3A4 INHIBITORS/SUVOREXANT (<= 10 MG)
  • MODERATE CYP3A4 INHIBITORS/AVANAFIL (<= 50 MG)
  • MODERATE CYP3A4 INHIBITORS/IBRUTINIB
  • SELECTED CYP3A4 INHIBITORS/VARDENAFIL (<= 5 MG)
  • APREPITANT; NETUPITANT/LURASIDONE (<= 80 MG)
  • SELECTED MODERATE CYP3A4 INHIBITORS/SELECTED OPIOIDS
  • MODERATE CYP3A4; P-GP INHIBITORS/EVEROLIMUS
  • MODERATE CYP3A4 INHIBITORS/RANOLAZINE (<=500 MG BID)
  • APREPITANT (>40 MG);NETUPITANT/SLT PO BENZODIAZEPINES
  • APREPITANT(>40MG);FOSAPREP/DEXAMETHASONE;METHYLPREDNISOLONE
  • SLT STRONG & MODERATE CYP3A4 INHIBITORS/CILOSTAZOL (<=50MG)
  • Free RX Coupon

    Save up to 80% on your prescriptions.

    Available coupons

    Save up to 80% on your prescription with WebMDRx

    Drug Survey

    Are you currently using Emend?

    This survey is being conducted by the WebMD marketing sciences department.

    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.