Estradiol Ring, Vaginal Side Effects by Likelihood and Severity

COMMON side effects


If experienced, these tend to have a Severe expression

  • Abnormally Long Or Heavy Periods
  • Bleeding Not Related To Menstrual Period
  • Breast Pain

If experienced, these tend to have a Less Severe expression

  • A Yeast Infection Of The Vagina And Vulva
  • An Infection
  • Backache
  • Breast Pain
  • Headache
  • Stomach Cramps
  • Swelling Of The Abdomen
  • Weight Gain

INFREQUENT side effects


If experienced, these tend to have a Less Severe expression

  • A Migraine Headache
  • Acne
  • Altered Interest In Having Sexual Intercourse
  • An Infection Due To The Fungus Candida
  • Cramps
  • Enlarged Breasts
  • Generalized Weakness
  • Headache
  • Inflammation Or Infection Of The Vagina
  • Itching
  • Pelvic Pain
  • Urinary Tract Infection
  • Uterine Cramps

RARE side effects


If experienced, these tend to have a Severe expression

  • A Bacterial Infection In Women Called Toxic Shock
  • A Blockage In The Gallbladder
  • A Blood Clot
  • A Breast Tumor
  • A Change In Vision
  • A Clot In The Lung
  • A Clot In The Small Veins That Carry Blood To Or From The Retina Of The Eye
  • A Heart Attack
  • A Hypersensitivity Reaction To A Drug
  • A Lump In The Breast
  • A Significant Type Of Allergic Reaction Called Anaphylaxis
  • A Stroke
  • A Type Of Allergic Reaction Called Angioedema
  • Blockage Of The Stomach Or Intestine
  • Blood Clot In A Deep Vein Of The Extremities
  • Cancer In The Lining Of The Uterus
  • Cancer Of The Ovary
  • Cancer Of The Uterus
  • Dementia
  • Diarrhea
  • Enlarged Breasts
  • Erythema Multiforme, A Type Of Allergic Skin Reaction
  • Erythema Nodosum, A Skin Condition With Red And Painful Nodules
  • Fluid Retention In The Legs, Feet, Arms Or Hands
  • Fluid Secretion From The Breast
  • High Amount Of Calcium In The Blood
  • High Amount Of Triglyceride In The Blood
  • High Blood Pressure
  • Inflammation Of The Gallbladder
  • Non-Cancerous Cysts Causing The Breast To Feel Lumpy
  • Obstruction Of A Blood Vessel By A Blood Clot
  • Overgrowth Of The Uterine Lining
  • Pancreatitis
  • Puberty At An Earlier Age Than Would Be Expected
  • Uterine Fibroids
  • Vaginal Irritation
  • Vaginal Ulcer
  • Weight Gain

If experienced, these tend to have a Less Severe expression

  • A Migraine Headache
  • Altered Interest In Having Sexual Intercourse
  • An Ovarian Cyst
  • Bleeding Not Related To Menstrual Period
  • Chest Pain
  • Depression
  • Diarrhea
  • Difficulty Sleeping
  • Dizziness
  • Fluid Secretion From The Breast
  • High Amount Of Calcium In The Blood
  • High Amount Of Triglyceride In The Blood
  • Hives
  • Itching
  • Itching Of The Genital Area
  • Mood Changes
  • Pain With Menstruation
  • Stomach Cramps
  • Vaginal Discharge
  • Vaginal Irritation
  • Vomiting
  • Water Retention
  • Yellow-Brown Patches On Skin

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.