Uses

What is trospium used for?

Trospium is commonly used to treat overactive bladder, when you have an urgent need to pee even if your bladder is not full, wetting accidents because of a strong need to pee, or frequent peeing.

Trospium may also be used for other conditions as determined by your healthcare provider.

How does trospium work (mechanism of action)?

Trospium increases the amount of pee that your bladder can hold by relaxing a muscle in your bladder.

How is trospium supplied (dosage forms)?

Trospium is available in the following dosage forms that are taken by mouth.

  • 60 mg extended-release oral capsules
  • 20 mg oral tablets

How should I store trospium?

Trospium should be stored at room temperature, between 68 F to 77 F (20 C to 25 C). It can be exposed to temperatures between 59 F to 86 F (15 C to 30 C) for shorter periods of time, such as when transporting it. Store in a cool, dry place.

Side Effects

What are the most common side effects of trospium?

The most common side effects of trospium are listed below. Tell your healthcare provider if you have any of these side effects that bother you.

  • Dry mouth
  • Constipation
  • Headache

There may be other side effects of trospium that are not listed here. Contact your healthcare provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088. In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.

What are the serious side effects of trospium?

While less common, the most serious side effects of trospium are described below, along with what to do if they happen.

Severe Allergic Reactions. Trospium may cause allergic reactions, which can be serious. Stop taking trospium and get help right away if you have any of the following symptoms of a serious allergic reaction.

  • Breathing problems or wheezing
  • Racing heart
  • Fever or general ill feeling
  • Swollen lymph nodes
  • Swelling of the face, lips, mouth, tongue, or throat
  • Trouble swallowing or throat tightness
  • Itching, skin rash, or pale red bumps on the skin called hives
  • Nausea or vomiting
  • Dizziness, feeling lightheaded, or fainting
  • Stomach cramps
  • Joint pain

Angioedema. Trospium may cause a rare reaction called angioedema. The usual symptoms of this reaction include swelling of the lips, face, tongue, or throat. Stop taking this medicine and contact your healthcare provider if you have this type of swelling. If you are having trouble breathing, get medical attention right away.

Inability to Empty Bladder (Urinary Retention). Trospium might make it harder to empty your bladder, especially if you already have a blockage or take other medicines for overactive bladder. Call your healthcare provider right away if you cannot empty your bladder.

Heat Exhaustion or Heat Stroke. Trospium can affect your ability to regulate your body temperature. This could make you become very hot, especially in hot weather. Call your healthcare provider right away if you are severely ill and have the following symptoms of heat-related illness.

  • Decreased sweating
  • Dizziness
  • Tiredness
  • Nausea
  • Increased body temperature

Warnings & Precautions

Who should not use trospium?

Allergies to Ingredients. People who are allergic to any of the following should not take trospium.

  • Trospium
  • Sanctura
  • Sanctura XR
  • Any of the ingredients in the specific product dispensed

Your pharmacist can tell you all of the ingredients in the specific trospium products they stock.

Inability to Empty the Bladder (Urinary Retention). Do not take trospium if you have a condition called urinary retention.

Slow Emptying of the Stomach (Gastric Retention). Do not take trospium if you have delayed or slow emptying of your stomach, a condition called gastric retention.

Glaucoma. Do not take trospium if you have uncontrolled narrow-angle glaucoma, a condition that causes increased pressure inside the eye.

What should I know about trospium before using it?

Do not take trospium unless it has been prescribed to you by a healthcare provider. Take it as prescribed.

Do not share trospium with other people, even if they have the same condition as you. It may harm them.

Keep trospium out of the reach of children.

Trospium can cause blurry vision, dizziness, and drowsiness. Do not drive or do other activities that require clear vision or alertness until you know how trospium affects you.

What should I tell my healthcare provider before using trospium?

Tell your healthcare provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if trospium is right for you.

In particular, make sure that you discuss any of the following.

  • Problems peeing, a weak urine stream, or a blockage in your bladder
  • Stomach or intestinal problems, or problems with constipation
  • Narrow-angle glaucoma
  • Myasthenia gravis
  • Kidney problems
  • Liver problems

Other Medicines and Supplements. Trospium may interact with other medicines and supplements. Before taking trospium, tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. See the Interactions section for more details.

Pregnancy. It is not known if or how trospium could affect pregnancy or harm an unborn baby. Tell your healthcare provider if you are or plan to become pregnant.

Breastfeeding. It is not known if trospium passes into breast milk. Tell your healthcare provider if you are breastfeeding or plan to breastfeed.

Interactions

Does trospium interact with foods or drinks?

Trospium should be taken on an empty stomach. Avoid taking trospium within 1 hour before a meal.

It is unknown if drinking alcohol will affect trospium. The risk of drowsiness may be increased if you drink alcohol while taking trospium. Do not drink alcohol within 2 hours of taking trospium.

Does trospium interact with other medicines (drug interactions)?

Trospium interacts with many other medicines. Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.

In particular, make sure that you discuss if you are using any of the following before using/taking [brand or generic name].

  • An anticholinergic medicine, which includes antihistamines and medicines commonly used for overactive bladder, Parkinson’s disease, or stomach problems
  • Metformin (Glucophage), which is a medicine commonly used to treat diabetes

This may not be a complete list of medicines that can interact with trospium. Always check with your healthcare provider.

Does Trospium (Sanctura) interact with other drugs you are taking?
Enter your medication into the WebMD interaction checker

Overdose/Missed Dose

What should I do if I accidentally use too much trospium?

If you or someone else has used too much trospium, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.

What should I do if I miss a dose of trospium?

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and only take the next dose. Do not take double or extra doses.