PHENYTOIN SODIUM Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • a toxic effect on the central nervous system, which consists of the brain and spinal cord
  • a hypersensitivity reaction to a drug

If experienced, these tend to have a Less Severe expression i

  • constipation
  • drowsiness
  • dizziness
  • nausea and vomiting

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • reactions at the site of the injection

If experienced, these tend to have a Less Severe expression i

  • abnormal forward position of one or both jaws
  • enlargement of the lips
  • enlarged breasts
  • hirsutism, a condition of hair growth on parts of the body normally without hair
  • difficulty sleeping
  • muscle twitching
  • taste impairment
  • headache

RARE side effects

If experienced, these tend to have a Severe expression i

  • a disorder of vitamin D
  • a disorder of the body's use of calcium
  • megaloblastic anemia
  • a type of blood disorder with a decrease in all types of blood cells called pancytopenia
  • decreased blood platelets
  • very low levels of granulocytes, a type of white blood cell
  • low levels of white blood cells
  • increased eosinophils in the blood
  • a blood disorder
  • involuntary movements of the limbs, trunk, and facial muscles called paroxysmal choreoathetosis
  • a type of slowed heart rhythm disorder called heart block
  • rapid ventricular heartbeat
  • ventricular fibrillation, a heart rhythm disorder
  • complete stoppage of the heart
  • slow heartbeat
  • abnormal heart rhythm
  • polyarteritis nodosa
  • significantly low blood pressure
  • x-ray results showing lung tissue changes
  • acute liver failure
  • inflammation of the liver called hepatitis
  • a blockage of the bile duct that resulting in high bilirubin levels
  • Peyronie's disease
  • inflammation of the skin with blisters
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • systemic lupus erythematosus, an autoimmune disease
  • a type of abnormal movement disorder called dyskinesia
  • swollen lymph nodes
  • a significant type of allergic reaction called anaphylaxis
  • a type of allergic reaction called angioedema
  • damage to the skin and tissue around the injection site
  • a type of bumpy skin rash called a maculopapular rash
  • multiple organ failure
  • abnormal muscle movements
  • purple glove syndrome, a skin condition where the extremities become swollen, purple and painful
  • a type of skin disorder called acute generalized exanthematous pustulosis
  • cerebellar atrophy
  • a type of significant allergic skin reaction called DRESS syndrome

If experienced, these tend to have a Less Severe expression i

  • a feeling of pins and needles on skin

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.