What Is a Prostate Biopsy?

A prostate biopsy is a when a doctor removes small samples of tissue from your prostate to test for cancer. Your doctor will order one if the results from a screening (a blood test or a digital rectal exam) show you might have prostate cancer.

This type of cancer is very common. An estimated 160,000 men will be diagnosed with it this year, and about 27,000 will die from it. Still, for most men, it often causes no problems or is easily treated. A biopsy can be an important part of diagnosis and treatment.

What Does My Prostate Do?

The prostate is beneath the bladder and in front of the rectum. It’s a walnut-shaped gland that surrounds part of the urethra. (That’s the tube that carries pee and semen out of the penis). Here’s what it does:

  • It produces fluid for semen, which includes sperm produced in the testicles.
  • It prevents urine from being included during ejaculation.

If it gets too big, your prostate can block semen or pee from passing through the urethra and out the penis.

When Do I Need a Biopsy?

Your doctor may order one if you’re showing symptoms of prostate cancer (difficulty peeing, blood in semen, problems getting or keeping an erection) or a blood test shows a high amount of prostate-specific antigen (PSA). He may also do a digital rectal exam, where he inserts a finger up your bottom to feel if your prostate is enlarged or has bumps. Another option before a biopsy is an ultrasound. Instead of a finger, a small probe is inserted to take pictures of the prostate.


The Procedure

Once your doctor decides to do a prostate biopsy, it's a simple, 10-minute procedure. He inserts a needle through the wall of your rectum and into the prostate to extract the cells for testing. Doctors usually take a dozen samples from various parts of the prostate.

The idea of such a procedure can make men nervous and it sounds painful. But the biopsy usually causes just brief discomfort. You may notice some blood in your pee and there could be some light bleeding from your bottom. There can also be blood in your semen. This can last for several weeks.

The sample will be sent to a lab, where they’ll be looked at under a microscope. It takes 3 days or so to get results back. If there’s cancer, you’ll be given something called a Gleason score. The higher your score, the more likely it is that your cancer will grow and spread quickly.

Since biopsies can miss the cancerous parts of the prostate, sometimes a repeat is ordered to be sure.

Treatment Options

If you and your doctor decide treatment is necessary, surgery to remove the prostate and nearby tissue is common if the cancer hasn’t spread.

Other treatment options include:

Some men with the disease might only need “active surveillance.” This means regular blood tests, rectal exams and possibly biopsies to keep an eye on things. If the cancer gets worse, you might discuss treatment options with your doctor.

WebMD Medical Reference Reviewed by William Blahd, MD on March 16, 2017



American Cancer Society: “Tests for Prostate Cancer; Key Statistics for Prostate Cancer;” “Surgery for Prostate Cancer;” “Treating Prostate Cancer; Cryotherapy for Prostate Cancer.”

Mayo Clinic: “Prostate cancer.”

Cleveland Clinic: “Prostate Cancer: Basics.”

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