6 New Migraine Treatments You Should Know About

You probably already use one or more of the many migraine treatments out there. They can work well. But they don’t always.

If you still find it hard to stop or prevent your headaches, you’ll want to know what else you can try.

New Devices

Cefaly is an electrical stimulation device. The FDA says it's effective and has few risks and side effects when used properly. It may help people who have problems with drug side effects.

You wear it like a headband across your forehead.

You can use it every day, but not more than once a day:

  • Apply the self-adhesive electrode to your forehead.
  • Connect the headband to the electrode. This starts the flow of electricity to a nerve linked to migraines.
  • You may feel a massaging or tingling sensation.
  • Wear it for 20 minutes. It shuts off automatically.

It’s the first TENS (transcutaneous electrical nerve stimulation) device approved for treating migraines before they start.

Other devices may be available. Ask your doctor.

CGRP Inhibitors

CGRP (calcitonin gene-related peptide) is a molecule involved in causing migraine pain. CGRP inhibitors are a class of drugs that block the effects of CGRP. Erenumab (Aimovig), galcanezumab (Emgality), and remanezumab (Ajovy) are approved to prevent migraine attacks. Depending on the drug, they’re taken monthly or quarterly by self-injection with a prefilled syringe or pen. Mild pain and redness at the injection site are the most common side effects. Less often, and in particular with galcanezumab, allergic reactions including itching, rash, hives, and trouble breathing that may require emergency care have been reported.



Your doctor might recommend this if you have chronic migraines.

About every 12 weeks, you get 31 Botox shots around your head and neck. Each session takes 10-15 minutes. After your first session, it may take 10-14 days for your symptoms to improve.

If you get migraines on fewer than 14 days a month or you get other types of headaches, Botox isn’t your answer.

Mild Anesthesia

SPG (sphenopalatine ganglion) nerve block. This short, simple procedure numbs the SPG, a group of nerve cells inside and behind your nose. The FDA has approved three devices for doing this.

It works because your SPG is linked to your trigeminal nerve, which is involved in these headaches.

You get the procedure in your doctor’s office. You’ll be awake for it.

Your doctor will insert a thin plastic tube, called a catheter, into your nose, one nostril at a time. Through an attached syringe, you’ll get an anesthetic to numb your SPG and the area around it. Your doctor may use an X-ray machine to be sure the tube is inserted correctly.

Once the numbness wears off, you may still feel relief for some time.


Several types of counseling can help.

In acceptance and commitment therapy (ACT), you accept that you have some migraine pain instead of trying to control it completely or avoid it.

You commit to “grow away” from a focus on migraines to discover goals and values you want more of in your life. And then you take action toward those goals.

Mindfulness-based therapy. “Mindfulness” is a practice of being aware of your mind and body right now. Distracting thoughts come up, but you let them go.

You may find that this helps you manage your migraine pain without being derailed by it. You might also feel less anxious or depressed about it.

You simply notice your thoughts, emotions, and body sensations.

You’ll still need your medicine and other treatments. Mindfulness is an additional practice you can do by yourself.

WebMD Medical Reference Reviewed by Arefa Cassoobhoy, MD, MPH on March 04, 2020


FDA: “Treating migraines: more ways to fight the pain.”
News releases, FDA.
American Headache Society: “Botox-A for suppression of chronic migraine: frequently asked questions.”
American Migraine Foundation: “Sphenopalatine ganglion blocks for headache disorders.”
Medscape.com: “Image-guided lidocaine injections for headache.”
National Headache Foundation: “New procedure may bring migraine relief.”
Smitherman, T. Current Pain Headache Reports, published online March 29, 2015.
Association for Contextual Behavioral Science: “A Short Guide to Acceptance and Commitment Therapy.”
American Headache Society: “Mindfulness meditation for migraine.”
Bromberg, J. Headache, 2012.

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