Skip to content

Chronic Kidney Disease

Font Size

Cause

The cause of chronic kidney disease isn't always known. But any condition or disease that damages blood vessels or other structures in the kidneys can lead to kidney disease. The most common causes of chronic kidney disease are:

  • Diabetes. High blood sugar levels caused by diabetes damage blood vessels in the kidneys. If the blood sugar level remains high over many years, this damage gradually reduces the function of the kidneys.
  • High blood pressure (hypertension). Uncontrolled high blood pressure damages blood vessels, which can lead to damage in the kidneys. And blood pressure often rises with chronic kidney disease, so high blood pressure may further damage kidney function even when another medical condition initially caused the disease.

Other conditions that can damage the kidneys and cause chronic kidney disease include:

Recommended Related to

10 Questions to Ask Your Doctor About Kidney Failure

If you were recently diagnosed with kidney failure, ask your doctor these questions at your next visit. What caused my kidney failure? Do I have hypertension, diabetes, or other disorders that may worsen my kidney failure? If I have an acute kidney problem, do you expect me to recover, and how long might that take? If my kidney problem is chronic, how long can I continue without dialysis, or will I ever need dialysis? What type of dialysis do you recommend? Am I a good ...

Read the 10 Questions to Ask Your Doctor About Kidney Failure article > >

  • Kidney diseases and infections, such as polycystic kidney disease, pyelonephritis, glomerulonephritis, or a kidney problem you were born with.
  • Having a narrowed or blocked renal artery. A renal artery carries blood to the kidneys.
  • Long-term use of medicines that can damage the kidneys. Examples include nonsteroidal anti-inflammatory drugs (NSAIDs), such as celecoxib and ibuprofen, and certain antibiotics.

Diabetes and high blood pressure are the most common causes of chronic kidney disease that leads to kidney failure. Diabetes or high blood pressure may also speed up the progression of chronic kidney disease in someone who already has the disease.

1

WebMD Medical Reference from Healthwise

Last Updated: August 29, 2013
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
Next Article:

Hot Topics

WebMD Video: Now Playing

Click here to wach video: Dirty Truth About Hand Washing

Which sex is the worst about washing up? Why is it so important? We’ve got the dirty truth on how and when to wash your hands.

Click here to watch video: Dirty Truth About Hand Washing

Popular Slideshows & Tools on WebMD

sore foot
3 warning signs.
acupuncture needle on shoulder
10 tips to look and feel good.
Epinephrine Injection using Auto-Injector Syringe
Life-threatening triggers.
disciplining a boy
Types, symptoms, causes.
psoriasis
What it looks like.
checking blood sugar
Symptoms and treatment.
man behind computer screen
10 possible causes.
Woman with itchy watery eyes
Common triggers.
man screaming
Making sense of symptoms.
human liver
What puts you at risk?
caregiver with parent
10 tips for daily life.
two male hands
Understanding RA.

Women's Health Newsletter

Find out what women really need.