Skip to content
    Font Size
    A
    A
    A

    Goodpasture Syndrome

    Goodpasture syndrome is a rare but serious autoimmune disease that attacks the lungs and kidneys.

    The disease occurs when the body's immune system mistakenly produces antibodies against collagen in the lungs and kidneys. Collagen is a protein that helps form connective tissue.

    Recommended Related to Health A-Z

    Swyer syndrome

    Important It is possible that the main title of the report Swyer syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

    Read the Swyer syndrome article > >

    Goodpasture syndrome initially causes vague symptoms such as fatigue. But it can rapidly involve the lungs and kidneys. It is almost always fatal if it is not quickly diagnosed and treated.

    Causes of Goodpasture Syndrome

    Researchers do not fully understand why the immune system attacks collagen in the lungs and kidneys. Goodpasture syndrome can run in families. So some researchers believe it may have a genetic component.

    Other factors that may increase the risk of Goodpasture syndrome include:

    • Exposure to certain chemicals, such as hydrocarbon solvents and the weed killer paraquat
    • Exposure to metallic dust
    • Use of certain drugs, such as cocaine
    • Tobacco smoking
    • Viral infections

    Goodpasture syndrome usually affects young men. It more often occurs among whites, and it most commonly affects people who are:

    • Between ages 20 and 30
    • Older than age 60

    Symptoms of Goodpasture Syndrome

    The first signs of Goodpasture syndrome may include:

    Because Goodpasture syndrome may rapidly involve the lungs, initial symptoms such as shortness of breath can quickly progress to a persistent cough, sometimes with blood.

    When Goodpasture syndrome affects the kidneys, symptoms may include:

    Although Goodpasture syndrome may cause life-threatening bleeding in the lungs, it usually does not result in long-term lung damage. The most serious consequence of Goodpasture syndrome is kidney failure, which may require either dialysis or a kidney transplant.

    Hot Topics

    WebMD Video: Now Playing

    Click here to wach video: Dirty Truth About Hand Washing

    Which sex is the worst about washing up? Why is it so important? We’ve got the dirty truth on how and when to wash your hands.

    Click here to watch video: Dirty Truth About Hand Washing

    Popular Slideshows & Tools on WebMD

    disciplining a boy
    Types, symptoms, causes.
    fruit drinks
    Eat these to think better.
    embarrassed woman
    Do you feel guilty after eating?
    diabetes highlighted
    4 early warning signs.
    handful of vegetables and vitamins
    Diet tips and mistakes.
    birth control pills
    Which kind is right for you?
    Remember your finger
    Are you getting more forgetful?
    sticky notes on face
    10 tips to clear your brain fog.
    Close up of eye
    12 reasons you're distracted.
    Trainer demonstrating exercise for RA
    Exercises for your joints.
    apple slices with peanut butter
    What goes best with workouts?
    woman having a good day
    Revitalize your life.

    Pollen counts, treatment tips, and more.

    It's nothing to sneeze at.

    Loading ...

    Sending your email...

    This feature is temporarily unavailable. Please try again later.

    Thanks!

    Now check your email account on your mobile phone to download your new app.

    Women's Health Newsletter

    Find out what women really need.