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Germ Cell Tumors

Treatment of a germinoma is usually radiation therapy. For treatment of a teratoma that has not spread, surgery is used. There is no standard treatment for other types of germ cell tumors.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with adult central nervous system germ cell tumor. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

Tumors of the Sellar Region: Craniopharyngioma

Treatment of craniopharyngiomas may include the following:

• Surgery to remove the whole tumor.
• Surgery to remove as much of the tumor as possible, followed by radiation therapy.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with adult craniopharyngioma. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

Recurrent Brain Tumors

Treatment of recurrentbrain tumors may include the following:

• Surgery with or without chemotherapy.
• Radiation therapy, if not used before, with or without chemotherapy.
• A second surgery followed by radiation therapy, if not used before, or chemotherapy.
• Internal radiation therapy.
• Chemotherapy.
• A clinical trial of a new anticancer drug with or without biologic therapy.
• A clinical trial of chemotherapy placed into the brain during surgery.
• A clinical trial of biologic therapy.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with recurrent adult brain tumor. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

Metastatic Brain Tumors

Treatment of a single tumor that has spread to the brain from another part of the body is usually surgery followed by radiation therapy to the whole brain.

Treatment of more than one tumor that has spread to the brain from another part of the body may include the following:

• Radiation therapy to the whole brain with or without stereotactic radiosurgery.
• Surgery, for tumors that are causing symptoms.
• Surgery to remove a tissue sample when the type of primary tumor is not known.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with tumors metastatic to brain. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.