Skip to content

Cancer Health Center

Font Size

Immunoglobulin - Overview

Immunoglobulin (also called gamma globulin or immune globulin) is a substance made from human blood plasma. The plasma, processed from donated human blood, contains antibodies that protect the body against diseases. When you are given an immunoglobulin, your body uses antibodies from other people's blood plasma to help prevent illness. And even though immunoglobulins are obtained from blood, they are purified so that they can't pass on diseases to the person who receives them.

Specific types of immunoglobulin are made to protect against specific diseases, such as hepatitis, chickenpox, or measles. Immunoglobulin injections may:

Recommended Related to Cancer

Late Effects of the Cardiovascular System

Radiation, chemotherapy, and biologic agents, both independently and in combination, increase the risk of cardiovascular disease in survivors of childhood cancer; in fact, cardiovascular death has been reported to account for 26% of the excess absolute risk of death by 45 or more years from diagnosis in adults who survived childhood cancers, and is the leading cause of noncancer mortality in select cancers such as Hodgkin lymphoma (HL).[1,2] During the 30 years after cancer treatment, survivors are...

Read the Late Effects of the Cardiovascular System article > >

  • Give short-term protection against or reduce the severity of certain diseases.
  • Protect your fetus if you are pregnant and at risk for Rh sensitization.
  • Decrease the immune system's ability to attack body tissues in some cases of autoimmune disease.
  • Help people who have an inherited problem making their own antibodies or those who are having treatment for certain types of cancer (such as leukemia). Treatments for some cancers can cause the body to stop producing its own antibodies, making immunoglobulin treatment necessary.

Disease prevention

You may be given an immunoglobulin if you are exposed to certain infectious diseases, such as hepatitis A, rubella, or measles. The immunoglobulin may prevent or reduce the severity of the illness if given shortly after exposure. The time period during which an injection provides this benefit ranges from days to months, depending on the disease.

Immunoglobulins do not provide long-term protection in the same way as a traditional vaccine. The protection they provide is short-term, usually lasting a few months. It is still possible to get the disease after the immunoglobulin has worn off.

Rh sensitization

When an Rh-negative woman becomes pregnant with an Rh-positive fetus (which can occur when the father's blood is Rh-positive), the pregnant woman's immune system makes antibodies that can destroy the fetus's blood in a future pregnancy. This antibody response is called Rh sensitization and occurs only if the fetus's blood mixes with the pregnant woman's, which can happen during birth.

To prevent Rh sensitization during pregnancy, you must have an Rh immunoglobulin injection if you are Rh-negative. This is done during your pregnancy and after delivery to protect the fetus of a future pregnancy.

    1|2
    Next Article:

    Today on WebMD

    Colorectal cancer cells
    A common one in both men and women.
    Lung cancer xray
    See it in pictures, plus read the facts.
     
    sauteed cherry tomatoes
    Fight cancer one plate at a time.
    Ovarian cancer illustration
    Do you know the symptoms?
     
    Jennifer Goodman Linn self-portrait
    Blog
    what is your cancer risk
    HEALTH CHECK
     
    colorectal cancer treatment advances
    Video
    breast cancer overview slideshow
    SLIDESHOW
     
    prostate cancer overview
    SLIDESHOW
    lung cancer overview slideshow
    SLIDESHOW
     
    ovarian cancer overview slideshow
    SLIDESHOW
    Actor Michael Douglas
    Article