Triptans and ditans are the most common medications prescribed for migraine headaches. They are most effective when taken early in an attack. They include almotriptan, eletriptan (Relpax), frovatriptan (Frova), lasmiditan (Reyvow), naratriptan (Amerge), rizatriptan (Maxalt) and sumatriptan (Imitrex, Onzetra Xsail, Sumavel, Tosymra, Zembrance) and zolmitriptan (Zomig). People with high blood pressure, heart disease, stroke, and other conditions may not be able to take triptans. And because of possible serious drug interactions, you should talk to your doctor about other medications you take, such as antidepressants or anti-seizure drugs. Side effects of triptans include nausea, dizziness, tingling, numbness, and chest pain.