For more information from the National Cancer Institute about multiple myeloma and other plasma cell neoplasms, see the following:
Multiple Myeloma/Other Plasma Cell Neoplasms Home Page
What You Need to Know About™ Multiple Myeloma
Drugs Approved for Multiple Myeloma and Other Plasma Cell Neoplasms
Targeted Cancer Therapies
Understanding Cancer Series: Targeted Therapies (Advances in Targeted Therapies and Targeted Therapies for Multiple Myeloma)
Bone Marrow Transplantation a...
Added text about the results of an analysis of Wilms tumor patients in the Surveillance, Epidemiology and End Results database that found that adults had a statistically worse overall survival than pediatric patients. Also added text to state that the investigators recommended that all adult patients diagnosed with Wilms tumor should undergo lymph node sampling and that there should be close collaboration with pediatric surgeons and oncologists in treatment planning (cited Kalapurakal et al. as reference 9, Reinhard et al. as reference 10, and Ali et al. as reference 11).
Added text to state that while little is known about the biology of clear cell sarcoma of the kidney, the t(10;17)(q22;p13) translocation has been reported in clear cell sarcoma of the kidney. As a result of the translocation, the YWHAE-FAM22 fusion transcript is formed; this was detected in 12% of clear cell sarcoma of the kidney cases in one series (cited O'Meara et al. as reference 16).
Treatment of Wilms Tumor
Added text about the results from a series of 49 patients with Wilms tumor who received preoperative therapy according to the SIOP-93-01 guidelines, and how the timing of surgery was determined when there was no longer imaging evidence of tumor regression (cited Sudour et al. as reference 15).
Added Adults with Wilms tumor as a new subsection.
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