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Healthy Women Lost More Than Twice as Much Weight on the Diet

April 15, 2003 -- There is new evidence that the popular but highly criticized very low-carbohydrate diets work and don't increase heart-disease risk factors -- at least in the short term.

In one of the first studies comparing low-fat and very low-carb approaches to weight loss, otherwise healthy obese women on carbohydrate restricted diets lost more than twice as much weight and significantly more body fat as women on a diet that restricted fat, even though both groups reported eating a similar number of calories each day.

Women eating the very low-carbohydrate diet lost an average of almost 19 pounds during the six-month study, compared with a loss of 8.5 pounds among the women eating a low-fat diet. Both groups saw improvements in blood pressure, cholesterol, and blood sugar and insulin levels.

Lead researcher Bonnie J. Brehm, PhD, RD, cautions that her short-term study, which included just 42 women, is far from the definitive word on whether a very low-carbohydrate diet is safe. But she says it is likely to spur more research into the diet made popular decades ago by the now famous diet guru Robert Atkins, MD.

"This study really produced more questions than answers," she says. "We don't know why the low-carb dieters lost so much more weight. We have no reason to believe that one group underreported their food consumption any more than another, and they reported eating about the same number of calories."

All the women participating in the study were told to maintain their pre-diet levels of exercise. But Brehm says the low-carb, high-protein dieters may have increased their activity levels without realizing it. Atkins proponents claim that people on the diet burn fat more quickly because carbohydrate restriction speeds up the metabolism. But Brehm, a University of Cincinnati dietitian, says there is little scientific evidence to back up the claim.

After decades of medical ridicule, the Atkins weight loss approach gained some credibility last summer with the release of widely publicized research from Duke University. Dieters in the Atkins-funded study lost an average of 20 pounds in six months, and also saw improvements in cholesterol and other cardiovascular risk factors.

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