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    Hirschsprung's Disease

    Important
    It is possible that the main title of the report Hirschsprung's Disease is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

    Synonyms

    • congenital megacolon
    • megacolon, aganglionic
    • colonic aganglionosis
    • HSCR
    • intestinal aganglionosis

    Disorder Subdivisions

    • None

    General Discussion

    Hirschsprung's disease (HSCR) is characterized by the absence of particular nerve cells (ganglions) in a segment of the bowel. The absence of ganglion cells causes the muscles to lose their ability to move the stool through the intestine (peristalsis). Constipation occurs and obstruction of the colon becomes more obvious and perhaps painful. HSCR can occur as an isolated problem or as part of disorder that affects multiple organ systems.

    Resources

    NIH/National Institute of Diabetes, Digestive & Kidney Diseases
    Office of Communications & Public Liaison
    Bldg 31, Rm 9A06
    31 Center Drive, MSC 2560
    Bethesda, MD 20892-2560
    Tel: (301)496-3583
    Email: NDDIC@info.niddk.nih.gov
    Internet: http://www2.niddk.nih.gov/

    International Foundation for Functional Gastrointestinal Disorders
    700 W. Virginia St., 201
    Milwaukee, WI 53217
    USA
    Tel: (414)964-1799
    Fax: (414)964-7176
    Tel: (888)964-2001
    Email: iffgd@iffgd.org
    Internet: http://www.iffgd.org

    Pull-Thru Network
    1705 Wintergreen Parkway
    Normal, IL 61761
    USA
    Tel: (309)262-2930
    Email: PullthruNetwork@gmail.com
    Internet: http://www.PullthruNetwork.org

    Bowel Group for Kids Inc.
    PO Box 40
    Oakdale, NSW, 2570
    Austrailia
    Tel: 02 4659 6067
    Fax: 61 2 4659 6381
    Email: enquiries@bgk.org.au
    Internet: http://www.bgk.org.au

    Genetic and Rare Diseases (GARD) Information Center
    PO Box 8126
    Gaithersburg, MD 20898-8126
    Tel: (301)251-4925
    Fax: (301)251-4911
    Tel: (888)205-2311
    TDD: (888)205-3223
    Internet: http://rarediseases.info.nih.gov/GARD/

    Madisons Foundation
    PO Box 241956
    Los Angeles, CA 90024
    Tel: (310)264-0826
    Fax: (310)264-4766
    Email: getinfo@madisonsfoundation.org
    Internet: http://www.madisonsfoundation.org

    CORE
    3 St. Andrews Place
    London, NW1 4LB
    United Kingdom
    Tel: 02074860341
    Fax: 02072242012
    Email: info@corecharity.org.uk
    Internet: http://www.corecharity.org.uk

    Medical Home Portal
    Dept. of Pediatrics
    University of Utah
    P.O. Box 581289
    Salt Lake City, UT 84158
    Tel: (801)587-9978
    Fax: (801)581-3899
    Email: mindy.tueller@utah.edu
    Internet: http://www.medicalhomeportal.org

    For a Complete Report:

    This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".

    The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

    It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

    This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

    For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

    Last Updated: 2/2/2008
    Copyright 1989, 1992, 1994, 1996, 1997, 2005 National Organization for Rare Disorders, Inc.

    WebMD Medical Reference from the National Organization for Rare Disorders

    Last Updated: May 28, 2015
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.

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