Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Mecamylamine may prevent beginning signs of ambenonium overdose. These signs include increased saliva, stomach pain, diarrhea, and nausea.
What might happen:
The initial signs of overdose may be hidden by the mecamylamine. Later signs of overdose include muscle twitching or paralysis.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know right away that you are taking these medicines together. Let your doctor know right away of you have any muscle twitching or paralysis.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
1.Mytelase (Ambenonium Chloride) US prescribing information. Sanofi-Aventis November, 2011.
2.Inversine (mecamylamine) US Prescribing Information. Targacept Inc. 7/02.