If you are:
Possibly Safe: INSUFFICIENT HUMAN DATA AVAILABLE
Possibly Safe: PROLONGED HYPOGLYCEMIA REPORTED; MFR REC. STOPPING 2 WKS BEFORE DELIVERY
Precaution: NO KNOWN INFANT ADVERSE OUTCOMES; MFR ADVISES CAUTION
Precaution: LIMITED DATA SUGGEST NEGLIGIBLE AMT EXCRETED W/NO RESULTING INFANT ADV EFFECT
An adult over 60:
management or monitoring precaution: Renal-Substantial renal clearance results in higher risk for severe, prolonged hypoglycemia in the elderly. Use lower initial and maintenance dose or consider other safer hypoglycemic agents.
management or monitoring precaution: Renal-Increased risk for drug induced metabolic acidosis with increasing age and declining renal function. Metformin is contraindicated in patients with an eGFR below 30 mL/min. Cardiovascular-Heart failure patients may have a higher risk for metabolic acidosis.
Giving Glucovance to a child under 12:
management or monitoring precaution: Safety and efficacy in pediatrics not established.
management or monitoring precaution: Safety and efficacy in pediatrics age < 10 years not established.