D.R. Betasone topical precautions What should I know regarding pregnancy, nursing and administering D.R. Betasone topical to children or the elderly?If you are: Pregnant: Only When Necessary: SYSTEMIC ABSORPTION UNKNOWN;POSSIBLE RISK OF OROFACIAL CLEFTS W/SYSTEMIC USE Nursing: Precaution: LEVEL OF TOPICAL DRUG ABSORPTION NOT KNOWN. An adult over 60: Giving D.R. Betasone topical to a child under 12: Relative Contraindication: RISK OF HPA-AXIS SUPPRESSION;GROWTH INHIBITION W/CHRONIC USE.