Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
When these two medicines are taken together, your body may process amprenavir more quickly.
What might happen:
The amount of amprenavir in your blood may decrease and it may not work as well against your HIV infection.
What you should do about this interaction:
Talk to your healthcare professional (e.g. doctor or pharmacist) as soon as possible about using a different form of birth control. Your doctor may want to check to see if you amprenavir is working.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.Reference:1.Agenerase (amprenavir) Oral Solution US prescribing information. GlaxoSmithKline May, 2005.