If you are:
FDB Only When Necessary: INSUF HUMAN DATA, ANIMAL DATA SUG DEV TOX;WEIGH TREATMENT BENEFIT VS FETAL RISK
Absolute Contraindication: INSUFF HUMAN DATA; POTENTIALLY HARMFUL TO INFANT BASED ON MECHANISM OF ACTION
An adult over 60:
management or monitoring precaution: General-Increased risk for severe side effects, including sepsis, deep thrombophlebitis, arterial thromboembolism, hypertension, hypotension, edema, MI, GI hemorrhage.
Giving bevacizumab Solution to a child under 12:
Severe Precaution: Non-mandibular osteonecrosis reported. No antitumor activity observed in relapsed glioblastoma study. No safety and efficacy established.