Some people are born with an increased tendency to form blood clots,
which increases their risk for developing blood clots in the legs (deep vein thrombosis) and in the lungs (pulmonary embolism). This tendency is due to inherited blood-clotting
irregularities, which are generally related to:
Mutated genes (such as factor V Leiden, factor
Decreased amounts of certain proteins (protein C, protein S,
and antithrombin III).
Increased levels of other substances
(antiphospholipid or lupus anticoagulant).
Many of these blood-clotting irregularities can be identified with
special tests. If your doctor suspects that you may have an
inherited blood-clotting irregularity, discuss whether testing is
It is possible that the main title of the report Von Willebrand Disease is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
This information is produced and provided by the National
Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National
Institute via the Internet web site at http://
.gov or call 1-800-4-CANCER.
WebMD Medical Reference from Healthwise
March 12, 2014
This information is not intended to replace the advice of a doctor.
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