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    Inherited Blood-Clotting Problems - Topic Overview

    Some people are born with an increased tendency to form blood clots. This makes them more likely to get blood clots in the legs (deep vein thrombosis) and in the lungs (pulmonary embolism). This tendency is due to inherited blood-clotting problems, which are often related to:

    • Mutated genes (such as factor V Leiden, factor II).
    • Decreased amounts of certain proteins. These may include protein C, protein S, and antithrombin III.
    • Increased levels of other substances. These may include antiphospholipid and lupus anticoagulant.

    Many of these blood-clotting irregularities can be found with special tests. If your doctor suspects that you may have an inherited blood-clotting problem, discuss whether you need testing.

    Recommended Related to DVT (Deep Vein Thrombosis)

    10 Questions to Ask Your Doctor About DVT

    1. What is DVT? And how dangerous is it? DVT stands for deep vein thrombosis, a blood clot in one of your body's deep veins, usually within a muscle of your leg. The biggest danger is that part of the clot could break off and travel to your lungs. It could cause a blockage known as a pulmonary embolism, or PE. Your doctor will talk to you about how likely that is to happen with your clot. 2. Are you sure I have a DVT? How is it diagnosed? People with a deep-vein clot in their leg...

    Read the 10 Questions to Ask Your Doctor About DVT article > >

    WebMD Medical Reference from Healthwise

    Last Updated: /2, 14 1
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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