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    Epilepsy and Multiple Subpial Transection (MST)

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    What Happens After Multiple Subpial Transection?

    After MST, the patient generally stays in an intensive care unit for 24 to 48 hours and in a regular hospital room for three to four days. Most people who have MST will be able to return to their normal activities, including work or school, in six to eight weeks after surgery. Most patients will continue to take anti-seizure medication. Once seizure control is established, medications may be reduced or eliminated.

    How Effective Is Multiple Subpial Transection?

    MST results in satisfactory improvement in seizure control in about 70% of patients, although the procedure is still relatively new, and no long-term outcome data are available. Children with LKS or other forms of epilepsy not controlled by medication may have improved intellectual and psychosocial functioning following MST.

    What Are the Side Effects of Multiple Subpial Transection?

    The following side effects may occur after MST, although they generally go away on their own over several weeks:

    • Scalp numbness
    • Nausea
    • Feeling tired or depressed
    • Headaches
    • Difficulty speaking, remembering, or finding words

    What Risks Are Associated With Multiple Subpial Transection?

    The risks associated with MST include:

    • Risks associated with surgery, including infection, bleeding, and an allergic reaction to anesthesia
    • Failure to relieve seizures
    • Swelling in the brain
    • Damage to healthy brain tissue

    WebMD Medical Reference

    Reviewed by Neil Lava, MD on July 20, 2014
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