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Erectile Dysfunction and Priapism

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Priapism is a persistent, usually painful, erection that lasts for more than four hours and occurs without sexual stimulation. The condition develops when blood in the penis becomes trapped and unable to drain. If the condition is not treated immediately, it can lead to scarring and permanent erectile dysfunction.

It can occur in all age groups, including newborns.

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There are two categories of priapism: low-flow and high-flow.

  • Low-flow: This type of priapism is the result of blood being trapped in the erection chambers. It often occurs without a known cause in men who are otherwise healthy, but also affects men with sickle-cell disease, leukemia (cancer of the blood), or malaria.
  • High-flow: High-flow priapism is more rare than low-flow and usually less painful. It is the result of a ruptured artery from an injury to the penis or the perineum (area between the scrotum and anus), which prevents blood in the penis from circulating normally.

What Causes Priapism?

  • Sickle cell anemia: Some cases of priapism are the result of sickle-cell disease. It has been estimated that approximately 42% of adults with sickle-cell disease will eventually develop priapism.
  • Medications: A common cause of priapism is the use and/or misuse of medications. Drugs that may cause priapism include Desyrel, used to treat depression, or Thorazine, used to treat certain mental illnesses. For people who have erectile dysfunction, oral or injection drugs used to treat the condition may also cause priapism.

Other causes of priapism include:

In rare cases, priapism may be related to cancers that can affect the penis and prevent the outflow of blood.

How Is Priapism Diagnosed?

If you experience priapism, it is important that you seek medical care immediately. Tell your doctor:

  • The length of time you have had the erection
  • How long your erections usually last
  • Any medication or drugs, legal or illegal, which you have used. Be honest with your doctor, illegal drug use is particularly relevant since both marijuana and cocaine have been linked to priapism.
  • Whether or not priapism followed trauma to that area of the body.

Your doctor will review your medical history and perform a thorough physical exam to determine the cause of priapism. This will include checking the rectum and the abdomen for evidence of unusual growths or abnormalities that may indicate the presence of cancer.

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