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Sleep Drug May Treat Fibromyalgia Pain

Study Shows Xyrem May Help Fight Pain and Fatigue in Fibromyalgia Patients

3 Drugs Approved for Fibromyalgia

There are three drugs approved in the U.S. for the treatment of fibromyalgia: Lyrica, Cymbalta, and Savella. None of them works in the same way as Xyrem.

By itself, each drug is effective in about 40% of patients, Clauw tells WebMD.

"So there is clearly room for other drugs with different mechanisms of action. Also, as with any chronic condition, you might get a better response by combining different drugs that work differently," he says. Clauw consults for the makers of all four drugs.

Kristine Thorson, a fibromyalgia patient from Tucson, Ariz., tells WebMD the drug worked when all others failed. "I was able to give up [narcotic painkillers]," she says.

At doses similar to those used in the treatment of narcolepsy, Xyrem can cost $500 a month.

Jazz Pharmaceuticals Inc., which makes the drug and funded the study, has applied for FDA approval for use of Xyrem in treating fibromyalgia.

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