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Heart Disease Health Center

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Cardiac Enzyme Studies

What To Think About

  • CK-MB, which is found in large amounts in damaged heart muscle is a more specific way to estimate the amount of heart muscle damage than total CK. The total CK enzyme level can be elevated from vigorous exercise, intramuscular injections, crush injuries to muscles, muscular dystrophy, or muscle inflammation.

Related Information


  1. Fischbach FT, Dunning MB III, eds. (2009). Manual of Laboratory and Diagnostic Tests, 8th ed. Philadelphia: Lippincott Williams and Wilkins.

Other Works Consulted

  • Chernecky CC, Berger BJ (2013). Laboratory Tests and Diagnostic Procedures, 6th ed. St. Louis: Saunders.

  • Fischbach FT, Dunning MB III, eds. (2009). Manual of Laboratory and Diagnostic Tests, 8th ed. Philadelphia: Lippincott Williams and Wilkins.

  • Thygesen K, et al. (2012). Third universal definition of myocardial infarction. Circulation, 126(16): 2020-2035. Also available online:

ByHealthwise Staff
Primary Medical ReviewerRakesh K. Pai, MD, FACC - Cardiology, Electrophysiology
Specialist Medical ReviewerGeorge Philippides, MD - Cardiology

Current as ofMarch 12, 2014

1 | 2 | 3

WebMD Medical Reference from Healthwise

Last Updated: March 12, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.

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