When Heartburn Gets Serious.
Esophagus Becomes Damaged, Possibly Pre-Cancerous
Ignoring heartburn -- just putting up with it, popping a few
pills day after day -- isn't necessarily the best plan. There are complications
that can result from letting the problem linger.
"When heartburn is not appropriately treated, acid reflux
can cause erosion and ulcers in the lining of the esophagus," says William
C. Orr, PhD, a clinical professor of medicine and specialist in
gastrointestinal disorders at the University of Oklahoma Health Sciences
"It's extremely painful and greatly affects the patient's
lifestyle," he tells WebMD. "It really alters very significantly the
quality of life."
Long-term acid reflux can cause scarring and narrowing in the
esophagus, which can also lead to swallowing difficulties, Radhika Srinivasan,
MD, a gastrointestinal specialist and assistant professor of medicine at the
University of Pennsylvania in Philadelphia, tells WebMD.
This condition, called esophageal strictures, can interfere
with eating and drinking by preventing food and liquid from reaching the
stomach. Strictures are treated by dilation, in which an instrument gently
stretches the strictures and expands the opening in the esophagus.
In fairly rare cases, chronic acid reflux can also cause a
pre-cancerous condition called "Barrett's esophagus," she adds.
Barrett's esophagus is a result of the chronic acid reflux into the esophagus
(swallowing tube) causing dangerous changes in the cells that line the
esophagus -- these cells can become cancerous.
The odds: If 100 people have heartburn on a regular basis for
many years, ten would have Barrett's esophagus; one out of those ten would
develop esophageal cancer.
Whether you are at risk depends on long you have had symptoms
and their frequency, Srinivasansays.
Thus, Barrett's esophagus is not a
condition to be taken lightly. The goal of treatment is to prevent further
damage by stopping any acid reflux from the stomach. Doctors give patients
proton pump inhibitor medications that block acid production like Aciphex,
Nexium, Protonix, Prevacid, and Prilosec. If these medications do not limit
to tighten the sphincter, or valve between the esophagus, and
stomach may be necessary.
In more severe cases, doctors use a
technique called ablation to destroy the abnormal tissue.