Hepatitis C is a sneaky virus. You may not have any symptoms at all. Most people don’t. Your doctor could check you liver and see only a little damage. You might not get diagnosed until he spots a problem with your liver enzymes after a routine blood test.
Although genotype tests are not used to diagnose HCV infection, they may be done before treatment begins. Knowing the genotype may help a doctor choose the best treatment plan. You should know your genotype before treatment starts.
The antiviral medicines peginterferon and ribavirin are more likely to work for people who have genotype 2 or 3. These medicines also are used to treat people who have genotypes 5 and 6.
Newer treatments for genotype 1 do not use peginterferon or ribavirin. A combination of sofosbuvir and simeprevir or a single pill containing ledipasvir and sofosbuvir can be used to treat hepatitis C in people who have genotype 1.
If blood tests show that you have responded to antiviral therapy (the virus is not detected in your blood) after 6 months, treatment may be:
Continued for another 6 months, if you are infected with genotype 1.
Stopped, if you are infected with genotype 2 or 3. Prolonging treatment does not seem to provide any more benefit.
The genotype of HCV does not appear to have any effect on the severity of HCV infection or to affect your risk of developing cancer of the liver.
In this article
This information is produced and provided by the National
Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National
Institute via the Internet web site at http://
.gov or call 1-800-4-CANCER.
WebMD Medical Reference from Healthwise
November 14, 2014
This information is not intended to replace the advice of a doctor.
Healthwise disclaims any liability for the decisions you make based on this