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Dehydration caused by a medicine

Many prescription and nonprescription medicines can cause dehydration or make it worse. At first you may feel thirsty, have a dry mouth, sticky saliva, and a reduced urine output with dark yellow urine. As dehydration gets worse, you may notice that your urine is very dark or concentrated, your mouth and eyes feel very dry, and you may feel faint when you stand up.

Medicines that can cause dehydration include:

  • Antihistamines, such as Benadryl and Chlor-Trimeton.
  • Blood pressure medicines, such as Tenormin, Lopressor, Capoten, or Calan.
  • Chemotherapy, such as cytoxan or 5-FU.
  • Diuretics, such as Lasix or Diuril.
  • Laxatives, such as Fleet Phospho-Soda or Correctol.
  • Psychiatric medicines, such as Risperdal or Seroquel.

If you think that your dehydration is caused by a medicine:

  • Call the doctor who prescribed the medicine to find out if you should stop taking it or take a different one. An appointment may not be necessary.
  • If you are taking a nonprescription medicine, stop taking it. Call your doctor if you feel you need to continue taking the medicine.
Author Jan Nissl, RN, BS
Editor Susan Van Houten, RN, BSN, MBA
Editor Sydney Youngerman-Cole, RN, BSN, RNC
Associate Editor Tracy Landauer
Primary Medical Reviewer William M. Green, MD
- Emergency Medicine
Specialist Medical Reviewer H. Michael O'Connor, MD
- Emergency Medicine
Last Updated July 6, 2007

WebMD Medical Reference from Healthwise

Last Updated: July 06, 2007
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.