Infertility and Men

Although some people still think of fertility as a "woman's problem," in 20% of infertile couples, the problem is solely with the male partner. Infertility in a man may be the only reason that a couple can't conceive, or it may simply add to the difficulties caused by infertility in his partner.

So it's crucial that men get tested for fertility as well as women. It's also important that men do it early. Though some guys may want to put off being tested -- possibly to avoid embarrassment -- early testing can spare their partners a great deal of unnecessary discomfort and expense. It's also a good way to quickly narrow down potential problems.

Getting Tested for Infertility

The first thing to do for fertility issues is to go to the doctor, typically a urologist. After a physical exam, your doctor will probably order a semen analysis, which will check the quality and quantity of the sperm in the semen. And yes, your doctor will want you to give the sample there, or at least someplace nearby, because it's important that the analysis takes place quickly. Just remember, as sheepish as you might feel, a semen analysis is a common test, and the results could save you months of worry and stress.

If the first semen analysis is normal, your doctor may order a second test to confirm the results. Two normal tests usually are interpreted to mean that the man doesn't have any significant infertility problems. If something in the results looks irregular, your doctor might order further tests to pinpoint the problem. At this point, if you aren't already seeing a urologist, you should considering seeing a specialist.

What a Semen Analysis Can Detect

  • Azoospermia. No sperm are produced, or the sperm aren't appearing in the semen.
  • Oligospermia. Few sperm are produced.
  • Problems with sperm motility; if sperm aren't moving normally, they are less likely to be capable of fertilizing an egg.
  • Problems with sperm morphology; problems with the form and structure -- or morphology -- of the sperm may cause infertility.

But while these conditions may be the direct reason that you can't conceive, they themselves may be caused by an underlying medical condition. Your doctor will probably want to investigate the issue further by ordering blood and urine tests or other procedures.

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Reasons for Male Infertility

There are a wide number of reasons for male infertility. Some are caused by physical problems that prevent the sperm from being ejaculated normally in semen. Others affect the quality and production of the sperm itself.

Possible Male Fertility Problems

  • Sexually transmitted diseases or other infections. Genital infections such as chlamydia and gonorrhea can cause infertility in men. The infertility can often be resolved by treating the infection.
  • Blockages, birth defects , or physical damage. In some cases, men are born with blockages in parts of the testicle or other abnormalities that prevent sperm from getting into the semen. Physical trauma to the testicles, prostate, and urethra can also result in fertility problems. Surgery can sometimes correct the problem.
  • Retrograde ejaculation. In this disorder, semen doesn't come out of the penis during ejaculation, but instead enters the bladder. It can be caused by diabetes, certain medications, and surgery to the bladder, prostate, or urethra.
  • Genetic diseases. Although it's rare, genetic illnesses such as cystic fibrosis or chromosomal disorders can cause infertility.
  • Autoimmune problems. In some cases, the immune system can mistakenly target sperm cells and treat them as if they were a foreign virus. The sperm can become damaged as a result.
  • Hormonal problems. Certain hormonal imbalances -- in the pituitary and thyroid glands, for instance -- can cause infertility. Your doctor may suggest treatment with medication.
  • Sexual problems. Erectile dysfunction (impotence) and premature ejaculation can obviously have an effect on fertility. Erectile dysfunction can be caused by psychological problems such as anxiety, guilt, or low self-esteem. It is also caused by physical problems such as diabetes, high blood pressure, high cholesterol, and heart disease. In addition, impotence may be a side effect of certain medications such as antidepressants. Talk to your doctor about ways of treating any sexual problems.
  • Varicoceles. Varicoceles are enlarged varicose veins that develop in the scrotum and prevent blood from flowing properly. Varicoceles are found in 15% of all men and in up to 40% of men being evaluated for infertility. Although they may be a factor in male infertility, recent studies question whether surgery to correct varicoceles has any beneficial effect.

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Other Factors in Male Infertility

  • Excessive exercise; studies have shown that exercising too much may lead to the release of too many steroid hormones. This can affect fertility.
  • Stress
  • Obesity
  • Use of drugs such as marijuana and cocaine, taking steroids, drinking alcohol, and smoking can reduce sperm counts.
  • Exposure to toxins and environmental hazards; pesticides, lead, radiation, radioactive substances, mercury, and heavy metals may affect fertility.
  • Heat; although the effect is usually temporary, high temperatures in the testicles could reduce sperm production. High heat could result from wearing clothing that's too tight and traps heat, frequent bike riding, or by taking too many hot baths or saunas.

Getting Pregnant With Male Infertility

If you're a guy who has been diagnosed with infertility, you should talk to your doctor about any behavorial changes you can make that might increase your chances of conceiving.

If your sperm count is low, your doctor may recommend having intercourse less frequently in order to build up a better concentration of sperm. You should also ask about taking vitamins. Some recent studies have found that men can improve their low sperm counts by taking a combination of a folic acid and zinc.

If you have abnormal hormone levels, your doctor may recommend hormone treatment.

If you have retrograde ejaculation, you can often treat this with common over-the-counter cold medicine.

In some cases where the man has mild infertility, artificial insemination or other assisted reproduction techniques, such as GIFT and ZIFT, may be helpful. One exciting treatment for male infertility and low sperm count is a form of micromanipulation called intracytoplasmic sperm injection (ICSI). This is a laboratory procedure in which sperm and eggs are retrieved from both partners, and then a single sperm is injected into an egg. The fertilized egg is then implanted into the woman's uterus.

If the man doesn't have sperm in his semen, one of several techniques can be used to retrieve sperm from the testicles. Success rates are generally good -- as high as 65% in some clinics. But factors such as poor sperm quality, poor egg quality, and the older age of the mother can lessen the chance of success. Other techniques that might help men with fertility problems are being developed.

WebMD Medical Reference Reviewed by Traci C. Johnson, MD on November 21, 2015

Sources

SOURCES: 
American Society for Reproductive Medicine web site. 
American College of Obstetricians and Gynecologists web site. 
WebMD Fertility Center web site. Human Reproduction Update, July-August 2002. 
The Infertility Workup and Understanding Treatment Options , RESOLVE online. 
The Merck Manual , Seventeenth Edition, 2000. 
The Fertility Handbook: A Guide to Getting Pregnant , Addicus Books, 2002.

American Urological Association web site: "Male Infertility."

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