Medicines to prevent tension headaches have not been well studied. The best evidence is for amitriptyline. It has been proven to reduce how often tension headaches occur and how bad they get.1 If you do not respond well to amitriptyline, you may try other tricyclic antidepressants, although they may not work as well to relieve your headache.
Side effects of tricyclic antidepressants include:
The U.S. Food and Drug Administration (FDA) has issued an advisory on antidepressant medicines and the risk of suicide. Talk to your doctor about these possible side effects and the warning signs of suicide.
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WebMD Medical Reference from Healthwise
May 02, 2014
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