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Schilder's Disease: Children & Multiple Sclerosis
What is Schilder's Disease?
Note: Schilder's disease is not the same as Addison-Schilder disease (adrenoleukodystrophy). Schilder's disease is a rare progressive demyelinating disorder which usually begins in childhood. Symptoms may include dementia, aphasia, seizures, personality changes, poor attention, tremors, balance instability, incontinence, muscle weakness, headache, vomiting, and vision and speech impairment. The disorder is a variant of multiple sclerosis.
Is there any treatment?
Treatment for the disorder follows the established standards in multiple sclerosis and includes corticosteroids, beta-interferon or immunosuppressive therapy, and symptomatic treatment.
What is the prognosis?
As with multiple sclerosis, the course and prognosis of Schilder's disease are unpredictable. For some individuals the disorder is progressive with a steady, unremitting course. Others may experience significant improvement and even remission. In some cases, Schilder's disease is fatal.
What research is being done?
The NINDS supports and conducts an extensive research program on demyelinating disorders such as Schilder's disease. Much of this research focuses on learning more about these disorders and finding ways to prevent, treat, and cure them.
Organizations
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National Multiple Sclerosis Society
733 Third Avenue 6th Floor New York, NY 10017-3288 nat@nmss.org http://www.nationalmssociety.org Tel: 212-986-3240 800-344-4867 (FIGHTMS) Fax: 212-986-7981 |
Multiple Sclerosis Association of America
706 Haddonfield Road Cherry Hill, NJ 08002 msaa@msaa.com http://www.msaa.com Tel: 856-488-4500 800-532-7667 Fax: 856-661-9797 |
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Multiple Sclerosis Foundation
6350 North Andrews Avenue Ft. Lauderdale, FL 33309-2130 support@msfocus.org http://www.msfocus.org Tel: 954-776-6805 888-MSFOCUS (673-6287) Fax: 954-351-0630 |
Related NINDS Publications and Information
Multiple Sclerosis: Hope Through Research
WebMD Public Information from the U.S. National Institutes of Health
Multiple Sclerosis Guide
ENABLEX is a prescription medicine used in adults to treat the following symptoms due to a condition called overactive bladder:
- · having a strong need to go to the bathroom right away (also called "urgency")
- · leaks or wetting accidents (also called "urinary incontinence")
- · having to go to the bathroom too often (also called "urinary frequency")
IMPORTANT SAFETY INFORMATION
You should not take once-daily ENABLEX if you have certain types of stomach problems, glaucoma, or have trouble emptying your bladder. Side effects of ENBLEX include blurred vision, and more commonly dry mouth, constipation, indigestion, and abdominal pain. Use caution when doing certain activities until you know how ENBALEX affects you.
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