If an ovarian growth is suspected, an ultrasound of the ovaries is done. If any abnormality is detected, further testing will be done. Tests include blood studies, CT scans, barium enema X-rays, colonoscopy, MRI, and chest X-rays to help evaluate the extent of the cancer. Ultimately, the surgical opening of the abdomen (exploratory laparotomy) is necessary to confirm or rule out an ovarian cancer diagnosis.
Genetic testing may be useful for women who have a family history of ovarian, uterine (endometrial), or breast cancer. This testing can reveal if you have inherited a gene mutation that is associated with increased risk of ovarian cancer. However, the presence (or lack) of these mutations does not necessarily predict whether you will go on to develop ovarian cancer. And, if you carry a mutation and want to take steps to help prevent ovarian cancer, you may consider removal of the ovaries.
Incidence and Mortality
Estimated new cases and deaths from ovarian cancer in the United States in 2013:
New cases: 22,240.
Several malignancies arise from the ovary. Epithelial carcinoma of the ovary is one of the most common gynecologic malignancies and the fifth most frequent cause of cancer death in women, with 50% of all cases occurring in women older than 65 years. Approximately 5% to 10% of ovarian cancers are familial, and three distinct hereditary...
Surgery is the standard treatment for ovarian cancer. Ordinarily, the two ovaries and the other reproductive organs are removed. Young women who have only a small tumor in one ovary and who still want to have children may have just the cancerous ovary removed; the second can be removed later to prevent cancer recurrence.
In most women with advanced disease, some cancer remains after surgery. A woman's prognosis depends on how much cancer remains and how well it responds to follow-up treatment. Most women receive chemotherapy, which can prolong survival and may result in a cure. Radiation therapy may be used to help alleviate symptoms or in certain patients with advanced disease. Even if no cancer is detected after treatment, follow-up exams are essential; women who have had the disease may be at greater risk for breast and colorectal cancer.
New chemotherapy drugs, biological drugs, and new methods of delivering treatment with fewer side effects, are being studied.