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LUTEIN

Other Names:

All-E-Lutein, All-E-Zeaxanthin, All-E-3'-dehydro-lutein, Beta,epsilon-carotene-3,3'-diol, Carotenoid, Caroténoïde, E-Lutein, Luteina, Lutéine, Lutéine Synthétique, Synthetic Lutein, Xanthophyll, Xanthophylle, Zeaxanthin, Zéaxanthine.

 Overview
 Uses
 Side Effects
 Interactions
 Dosing
Overview Information

Lutein is called a carotenoid vitamin. It is related to beta-carotene and vitamin A. Foods rich in lutein include broccoli, spinach, kale, corn, orange pepper, kiwi fruit, grapes, orange juice, zucchini, and squash. Lutein is absorbed best when it is taken with a high-fat meal.

Many people think of lutein as “the eye vitamin.” They use it to prevent eye diseases including age-related macular degeneration (AMD), cataracts, and retinitis pigmentosa.

Some people also use it for preventing coloncancer, breastcancer, type 2 diabetes, and heart disease.

Many multivitamins contain lutein. They usually provide a relatively small amount of 0.25 mg per tablet.

How does it work?

Lutein is one of two major carotenoids found as a color pigment in the human eye (macula and retina). It is thought to function as a light filter, protecting the eye tissues from sunlight damage.

Uses & Effectiveness What is this?

Likely Effective for:

  • Lutein deficiency. Taking lutein by mouth is effective for preventing lutein deficiency.

Possibly Effective for:

  • An eye disease called age-related macular degeneration (AMD). Population studies suggest that people who consume higher amounts of lutein in their diet have a reduced risk of developing AMD. However, increasing dietary intake of lutein might not reduce the risk of AMD in people who already have a high intake of lutein. Taking lutein supplements for up to 12 months can improve some symptoms of AMD, but it does not seem to prevent AMD from becoming worse. Research on the use of lutein together with other ingredients shows conflicting results.
  • Cataracts. Some studies suggest that eating higher amounts of lutein might decrease the risk of developing cataracts. Also, early research suggests that taking lutein three times weekly for up to 2 years can improve vision in elderly people with cataracts.

Possibly Ineffective for:

  • Clogged arteries (coronary heart disease). Research suggests that eating higher amounts of lutein does not lower the risk of developing clogged arteries.

Insufficient Evidence for:

  • Breast cancer. Some evidence suggests that higher levels of lutein in the blood are linked with a reduced risk of developing breast cancer.
  • Cervical cancer. Early research suggests that low amounts of lutein in the diet are not linked with an increased risk of developing cervical cancer.
  • An inherited condition that causes vision loss (choroideremia). Early research suggests that taking 20 mg of lutein daily for 6 months does not improve vision in people with choroideremia.
  • Mental function. Some early research suggests that taking 12 mg of lutein plus 800 mg of docosahexaenoic acid (DHA) for 4 months can improve speaking and memory in older women.
  • Colon and rectal cancer. There is conflicting results about whether diets containing higher amounts of lutein can reduce the risk of developing colon or rectal cancer.
  • Diabetes. Some research suggests that low blood levels of lutein or other carotenoids are linked with blood sugar problems. In theory, taking lutein might reduce the risk of developing diabetes. However, other research suggests that increasing lutein intake in the diet does not reduce the risk of developing diabetes.
  • Muscle soreness after exercise. Some evidence suggests that taking a combination product that contains lutein (BioAstin) daily for 3 weeks before exercise does not reduce muscle soreness after exercise.
  • Eye strain (asthenopia). Early research suggests that some taking lutein along with other supplements might reduce eye strain. The effect of lutein alone on eye strain is unclear.
  • Lung cancer. Some evidence suggests that low blood levels of lutein are linked with an increased risk of developing lung cancer. However, other evidence suggests that taking lutein does not affect the risk of developing or dying from lung cancer.
  • High blood pressure during pregnancy. Some research suggests that high blood levels of lutein are linked with a lower risk of developing high blood pressure during pregnancy. It is not clear if taking lutein supplements lowers the risk of high blood pressure during pregnancy.
  • Prostate cancer. Some research shows that low blood levels of lutein are not linked with an increased risk of prostate cancer.
  • Respiratory infections. Some research shows that high blood levels of lutein are not linked with a decreased risk of respiratory infections
  • An eye disease called retinitis pigmentosa. Some early evidence suggests that lutein might be helpful in the treatment of retinitis pigmentosa. However, other evidence suggests that lutein does not improve vision or other symptoms of this eye disease.
  • Eye problems in premature infants (retinopathy of prematurity). Early research suggests that lutein does not decrease the risk or severity of retinopathy of prematurity.
  • Other conditions.
More evidence is needed to rate the effectiveness of lutein for these uses.


Side Effects & Safety

Lutein is LIKELY SAFE when taken by mouth appropriately. Consuming 6.9-11.7 mg/day of lutein as part of the diet appears to be safe. Lutein supplements have been used safely in studies in doses up to 15 mg daily for up to 2 years.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Lutein is LIKELY SAFE when used in the amounts found in food.

Cystic fibrosis: People with cystic fibrosis might not absorb some carotenoids from food very well, and often have low blood levels of lutein. How much the body absorbs from lutein supplementation might also be decreased in people with cystic fibrosis.

Interactions What is this?

We currently have no information for Interactions

Dosing

The following doses have been studied in scientific research:

BY MOUTH:

  • For reducing the risk of cataracts and age-related macular degeneration (AMD): 6 mg of lutein per day, either through diet or using supplements. People consuming 6.9 to 11.7 mg of lutein per day through diet had the lowest risk of developing AMD and cataracts.
  • For reducing symptoms of AMD: 10 mg per day of lutein supplements.
There is 44 mg of lutein per cup of cooked kale, 26 mg/cup of cooked spinach, and 3 mg/cup of broccoli.

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Conditions of Use and Important Information: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2009.

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