Overview
Trivalent chromium is found in foods and supplements. It might help keep blood sugar levels normal by improving the way the body uses insulin.
People use chromium for chromium deficiency. It is also used for diabetes, high cholesterol, athletic performance, bipolar disorder, and many other purposes, but there is no good scientific evidence to support most of these uses.
This topic only covers trivalent chromium, not hexavalent chromium.
Uses & Effectiveness ?
Likely Effective for
- Chromium deficiency. Taking chromium by mouth is effective for preventing chromium deficiency.
Possibly Effective for
- Diabetes. Taking chromium by mouth might improve blood sugar control in some people with type 2 diabetes. Higher chromium doses seem to work better than lower doses. It's not clear if it helps prevent diabetes.
Possibly Ineffective for
- High blood pressure. Taking chromium by mouth does not appear to lower blood pressure.
- Prediabetes. Taking chromium by mouth doesn't help control blood sugar levels in people with prediabetes.
- Schizophrenia. Taking chromium by mouth doesn't affect weight or mental health in people with schizophrenia.
Side Effects
Some people experience side effects such as stomach upset, headaches, insomnia, and mood changes. High doses have been linked to more serious side effects including liver or kidney damage.
Special Precautions and Warnings
Some people experience side effects such as stomach upset, headaches, insomnia, and mood changes. High doses have been linked to more serious side effects including liver or kidney damage.
Pregnancy: Chromium is likely safe when taken by mouth in amounts that do not exceed adequate intake (AI) levels. The AI for those 14-18 years old is 28 mcg daily. For those 19-50 years old, it is 30 mcg daily. Chromium is possibly safe to use in amounts higher than the AI levels while pregnant. But don't take chromium supplements during pregnancy unless advised to do so by a healthcare provider.
Breast-feeding: Chromium is likely safe when taken by mouth in amounts that do not exceed AI levels. The AI for those 14-18 years old is 44 mcg daily. For those 19-50 years old, it is 45 mcg daily. There isn't enough reliable information to know if taking higher amounts of chromium is safe when breast-feeding. Stay on the safe side and stick with amounts below the AI.
Children: Chromium is likely safe when taken by mouth in amounts that don't exceed AI levels. For those 0-6 months old, it is 0.2 mcg; for those 7-12 months old, it is 5.5 mcg; for those 1-3 years old, it is 11 mcg; for those 4-8 years old, it is 15 mcg. For males 9-13 years old, it is 25 mcg; for males 14-18 years old, it is 35 mcg. For females 9-13 years old, it is 21 mcg; for females 14-18 years old, it is 24 mcg. Taking chromium in amounts above the AI level is possibly safe for most children.
Behavioral or psychiatric conditions such as depression, anxiety, or schizophrenia: Chromium might affect brain chemistry and might make behavioral or psychiatric conditions worse.
Chromate/leather contact allergy: Chromium supplements can cause allergic reactions in people with chromate or leather contact allergy. Symptoms include redness, swelling, and scaling of the skin.
Kidney disease: Chromium supplements might cause kidney damage. Don't take chromium supplements if you have kidney disease.
Liver disease: Chromium supplements might cause liver damage. Don't take chromium supplements if you have liver disease.
Interactions ?
Insulin interacts with CHROMIUM
Chromium might increase how well insulin works. Taking chromium along with insulin might cause your blood sugar to drop too low. Monitor your blood sugar closely. The dose of your insulin might need to be changed.
Levothyroxine (Synthroid, others) interacts with CHROMIUM
Taking chromium with levothyroxine might decrease how much levothyroxine the body absorbs. This might make levothyroxine less effective. To help avoid this interaction, levothyroxine should be taken 30 minutes before or 3-4 hours after taking chromium.
Medications for diabetes (Antidiabetes drugs) interacts with CHROMIUM
Chromium might lower blood sugar levels. Taking chromium along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely.
Moderate Interaction
Be cautious with this combination
NSAIDs (Nonsteroidal anti-inflammatory drugs) interacts with CHROMIUM
NSAIDs might increase chromium levels in the body and increase the risk of adverse effects. Avoid taking chromium supplements and NSAIDs at the same time.
Aspirin interacts with CHROMIUM
Aspirin might increase how much chromium the body absorbs. Taking aspirin with chromium might increase the effects and side effects of chromium.
Minor Interaction
Be watchful with this combination
Dosing
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