Uses

What is Varivax used for?

Varivax (varicella virus vaccine live) is commonly given to help prevent chickenpox, a very contagious infection caused by the varicella-zoster virus.  

How does Varivax work (mechanism of action)?

Varivax is made from a live, weakened form of the varicella virus. It triggers the body’s immune response to make a type of protein (antibodies) against varicella-zoster virus, the virus that causes chickenpox. If you have antibodies against this virus, your body is better able to fight it, which may help you from getting sick. 

How should I store Varivax?

Varivax is usually given by a healthcare provider in a pharmacy, hospital, or clinic. You will not store it at home.

Side Effects

What are the most common side effects of Varivax?

The most common side effects of Varivax are listed below. Tell your healthcare provider if you have any of these side effects that bother you.

  • Fever
  • Pain, itching, swelling, or redness near the injection site 
  • Feeling irritable
  • Rash that looks like chickenpox on the body or near the injection site
  • Headache
  • Tiredness

There may be other side effects of Varivax that are not listed here. Contact your healthcare provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088. In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.

What are the serious side effects of Varivax?

While less common, the most serious side effects of Varivax are described below, along with what to do if they happen.

Severe Allergic Reactions. Varivax may cause allergic reactions, which can be serious. Get help right away if you have any of the following symptoms of a serious allergic reaction.

  • Breathing problems or wheezing
  • Racing heart
  • Fever or general ill feeling
  • Swollen lymph nodes
  • Swelling of the face, lips, mouth, tongue, or throat
  • Trouble swallowing or throat tightness
  • Itching, skin rash, or pale red bumps on the skin called hives
  • Nausea or vomiting
  • Dizziness, feeling lightheaded, or fainting
  • Stomach cramps
  • Joint pain

Warnings & Precautions

Who should not get Varivax?

Allergies to Ingredients. People who are allergic to any of the following should not receive Varivax.

  • Gelatin
  • Neomycin
  • Varivax
  • Varicella virus vaccine live
  • A previous dose of varicella-containing vaccine
  • Any of the ingredients in the specific product dispensed

Your pharmacist can tell you all of the ingredients in Varivax.

Weakened Immune System (Immunosuppression). Varivax should not be given to people who have a weakened immune system or who are immunocompromised due to a health condition or a medicine. This includes people who are receiving high doses of steroids or who are being treated with certain types of chemotherapy. There is a risk that live varicella vaccine could cause varicella infection in people with a weakened or suppressed immune system.      

Moderate or Severe Illness With Fever (Febrile Illness). Varivax should not be given to people with a fever greater than 101.3 F (38.5 C). 

Active Untreated Tuberculosis (TB). People with tuberculosis who have symptoms but are not receiving medicine to treat the condition should not receive Varivax. 

Pregnancy. Do not receive Varivax if you are pregnant or planning to become pregnant in the next 3 months. If you become pregnant, contact your healthcare professional right away. See the Pregnancy section for more details.

What should I know about Varivax before getting it?

Varivax is a shot that must be administered by a healthcare provider. The vaccine is injected into the muscle or under the skin. 

A vaccine information statement should be provided by your healthcare provider to you before each vaccination. This document provides information regarding the benefits and risks of the vaccine.

Make sure that you or your child gets all doses of Varivax that your healthcare provider recommends. Varivax helps protect you from serious infections caused by the varicella-zoster virus. 

Children ages 12 months through 17 years of age should avoid taking medicines or other products that contain salicylates such as aspirin for 6 weeks after receiving Varivax. There are reports of Reye’s syndrome in people taking salicylates while infected with chickenpox. See the Interactions section for more details.

In rare cases, a person who has received Varivax may be able to pass varicella vaccine virus to others after vaccination. This can lead to chickenpox, including severe cases, in people who have not had chickenpox or Varivax. For 6 weeks after getting Varivax, avoid close contact with people who are at high risk of developing chickenpox. People who are at high risk of chickenpox are those with a weakened immune system, pregnant people who have not had chickenpox, and newborn babies born at less than 28 weeks of pregnancy or to mothers who have not had chickenpox.

What should I tell my healthcare provider before getting Varivax?

Tell your healthcare provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if Varivax is right for you.

In particular, make sure that you discuss any of the following.

Blood Transfusions. Varivax should not be given at the same time as immune globulins (IG) or other blood products. These products may contain antibodies that interfere with how the vaccine works in the body.  Before getting Varivax, tell your healthcare provider about any immune globulins or blood or plasma transfusions you may have received. 

Vaccines. Tell your healthcare provider if you have recently received a vaccine or have any scheduled. Varivax can usually be administered on the same day as other vaccines. In some cases, Varivax may need to be spaced apart from other vaccines by a certain length of time. 

Reactions to Vaccines. Before getting Varivax, tell your healthcare provider if you have had an allergic reaction to any other vaccine or other serious symptoms such as fainting or dizziness after vaccination.

Tuberculin Skin Testing (TB testing). Before getting Varivax, tell your healthcare provider if you are scheduled to be tested for tuberculosis. Varivax may interfere with the results of skin tests.

Other Medicines and Supplements. Varivax may interact with other medicines and supplements. Before getting Varivax, tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. See the Interactions section for more details.

Family History of Immune System Problems (Immunodeficiency). There is a risk that Varivax could cause varicella infection in people with a weakened or suppressed immune system. Tell your healthcare provider if you have a family history of immune system problems. This information will help them determine if Varivax is right for you.

Close Contact With People at Risk of Developing Chickenpox. In rare cases, a person who has received Varivax may be able to pass varicella vaccine virus to others following vaccination. Tell your healthcare provider if you or your child lives or works with someone who falls into one of the below groups of people. 

  • People who have a weakened immune system
  • Pregnant people who have not had chickenpox
  • Newborn babies of mothers who have not had chickenpox
  • Newborn babies born at less than 28 weeks of pregnancy

Current and Past Health Conditions. Tell your healthcare provider if you have any of the following.

  • Cancer
  • HIV
  • Tuberculosis (TB)
  • Any health condition that weakens the immune system
  • Health conditions requiring use of salicylates such as aspirin

Pregnancy. Do not receive Varivax and tell your healthcare provider if you are or plan to become pregnant. Varivax may cause harm to an unborn baby.

Breastfeeding. It is not known if Varivax passes into breast milk. Tell your healthcare provider if you are breastfeeding or plan to breastfeed. Your healthcare provider will advise you if you should get Varivax while breastfeeding.

How can I get more information about Varivax?

For more information about Varivax, you can visit the manufacturer’s website at https://www.merckvaccines.com/varivax/ or call them at 800-637-2590 or 800-982-7482.

Interactions

Does Varivax interact with foods or drinks?

There are no known interactions between Varivax and foods or drinks.

It is unknown if drinking alcohol will affect Varivax. 

Does Varivax interact with other medicines (drug interactions)?

Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. Tell your healthcare provider if you have received any vaccines in the past 4 weeks or have any vaccines scheduled.

In particular, make sure that you discuss if you are using or have received any of the following before getting Varivax.

  • Aspirin, which is in many prescription and OTC products including those for pain, swelling, and fever
  • Bismuth subsalicylate, a medicine used to treat diarrhea, heartburn, and upset stomach
  • Magnesium salicylate or other medicines or supplements containing salicylates
  • A corticosteroid, which is a medicine for certain inflammatory conditions
  • Medicines that weaken the immune system
  • Immune globulins or blood transfusions
Does Varivax (varicella virus vaccine live) interact with other drugs you are taking?
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Overdose/Missed Dose

What should I do if I accidentally receive too much Varivax?

Varivax is given by a healthcare provider. Keep a record of all vaccines you receive and share it with your healthcare provider. If you have any side effects, please report them by calling 800-822-7967 or filling out an online form at https://vaers.hhs.gov.

What should I do if I miss a dose of Varivax?

Keep all appointments to receive Varivax. If you miss an appointment to get Varivax, call to make another appointment as soon as possible.

Drug Survey

Are you currently using Varivax (varicella virus vaccine live)?

This survey is being conducted by the WebMD marketing sciences department.