If you are:
Only When Necessary: PER HEALTH CANADA POSSIBLE NEWBORN SIDE EFFECTS APPEAR LESS THAN W/ SNRI, SSRI'S
Precaution: POSSIBLE SEDATION; LONG TERM NEURO EFFECTS UNKNOWN
An adult over 60:
management or monitoring precaution: Neuro/Psych-Elderly at risk for over-sedation resulting in confusion. Endocrine-May exacerbate or cause SIADH and hyponatremia. Cardiovascular-Orthostatic hypotension risk. Renal-Decrease dose for CrCL< 30 mL/min. Hepatic-In combination with renal impairment, may require dose adjustment.
Giving mirtazapine to a child under 12:
Severe Precaution: Possible increased suicidal ideation and suicide attempts. Efficacy not established in pediatrics. Not approved for pediatric use per manufacturer.