If you are:
Only When Necessary: NEONATAL WITHDRAWAL/RESP.DEPRESS. W/CHRONIC OR HIGH DOSE; SMALL TERATOGENIC RISK
Precaution: INSUFFICIENT DATA AVAIL; LOW LEVELS EXCRETED WITH SHORT TERM USE
An adult over 60:
management or monitoring precaution: Pulmonary-DO NOT USE in opioid intolerance. Life-threatening respiratory depression more likely to occur due to altered clearance. Use cautiously with respiratory disease, when initiating, titrating and giving with other respiratory depressants. Neuro/Psych-Risk for confusion, delirium and falls. Avoid treatment with 3 or more CNS active agents. Gastrointestinal-Increased rate of constipation in the elderly. Cardiovascular-Vasodilation may predispose to orthostatic hypotension.
Giving Duragesic Patch, Transdermal 72 Hours to a child under 12:
Severe Precaution: Administration restricted to opioid tolerant patients. Risk of severe respiratory depression.
Contraindication: Safety not established age < 2 years. Risk of fatal respiratory depression in opioid-naive.